Structural highlights
Function
RLMM_ECOLI Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA. Modifies C2498 in naked 23S rRNA, but not in assembled 50S subunits or ribosomes.[1] [2]
References
- ↑ Purta E, O'Connor M, Bujnicki JM, Douthwaite S. YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA. Mol Microbiol. 2009 Jun;72(5):1147-58. doi: 10.1111/j.1365-2958.2009.06709.x., Epub 2009 Apr 28. PMID:19400805 doi:http://dx.doi.org/10.1111/j.1365-2958.2009.06709.x
- ↑ Punekar AS, Shepherd TR, Liljeruhm J, Forster AC, Selmer M. Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA. Nucleic Acids Res. 2012 Aug 25. PMID:22923526 doi:http://dx.doi.org/10.1093/nar/gks727