Structural highlights
Publication Abstract from PubMed
The crystal structure of the decamer sequence d(CCGGGACCGG)(4) has previously been reported at 2.16 A resolution as a four-way junction. Here, the structure of this sequence is reported at the significantly higher resolution of 1.6 A, which is the highest resolution reported for a four-way junction. This allowed the unambiguous identification of an extensive hydration network with distinct patterns and solvent-mediated interactions that shed new light on the role of water in the formation and stabilization of junction structures.
Structure of d(CCGGGACCGG)(4) as a four-way junction at 1.6 A resolution: new insights into solvent interactions.,Chakraborty A, Mandal PK, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1169-74., doi: 10.1107/S1744309112034926. Epub 2012 Sep 25. PMID:23027741[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Chakraborty A, Mandal PK, Gautham N. Structure of d(CCGGGACCGG)(4) as a four-way junction at 1.6 A resolution: new insights into solvent interactions. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1169-74., doi: 10.1107/S1744309112034926. Epub 2012 Sep 25. PMID:23027741 doi:http://dx.doi.org/10.1107/S1744309112034926