Structural highlights
Function
BTRN_NIACI Catalyzes the radical S-adenosyl-L-methionine (SAM)-dependent two-electron oxidation of 2-deoxy-scyllo-inosamine (DOIA) to amino-dideoxy-scyllo-inosose (amino-DOI) in the biosynthetic pathway of butirosin.[1]
References
- ↑ Yokoyama K, Numakura M, Kudo F, Ohmori D, Eguchi T. Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin. J Am Chem Soc. 2007 Dec 12;129(49):15147-55. doi: 10.1021/ja072481t. Epub 2007 , Nov 15. PMID:18001019 doi:http://dx.doi.org/10.1021/ja072481t