Structural highlights
Function
POXIN_NPVAC Nuclease that cleaves host 2',3'-cGAMP.[HAMAP-Rule:MF_04143][1]
References
- ↑ Eaglesham JB, Pan Y, Kupper TS, Kranzusch PJ. Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling. Nature. 2019 Feb;566(7743):259-263. doi: 10.1038/s41586-019-0928-6. Epub 2019 Feb, 6. PMID:30728498 doi:http://dx.doi.org/10.1038/s41586-019-0928-6