Structural highlights
Function
GP_TSWV1 Forms the spikes present at the surface of the virion together with Glycoprotein C. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity). Plays a role in virus binding and/or entry into the vector midgut (PubMed:31413126).[UniProtKB:P08668][1] Forms the spikes present at the surface of the virion together with Glycoprotein N. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity). Probable class II fusion protein (PubMed:33672327).[UniProtKB:P08668][2]
References
- ↑ Badillo-Vargas IE, Chen Y, Martin KM, Rotenberg D, Whitfield AE. Discovery of Novel Thrips Vector Proteins That Bind to the Viral Attachment Protein of the Plant Bunyavirus Tomato Spotted Wilt Virus. J Virol. 2019 Oct 15;93(21):e00699-19. PMID:31413126 doi:10.1128/JVI.00699-19
- ↑ Hulswit RJG, Paesen GC, Bowden TA, Shi X. Recent Advances in Bunyavirus Glycoprotein Research: Precursor Processing, Receptor Binding and Structure. Viruses. 2021 Feb 23;13(2):353. PMID:33672327 doi:10.3390/v13020353