Structural highlights
Function
A0A0M5I297_STRHE
Publication Abstract from PubMed
Strigolactones (SLs) regulate many aspects of plant development, but ambiguities remain about how this hormone is perceived because SL-complexed receptor structures do not exist. We find that when SL binds the Striga receptor, ShHTL5, a series of conformational changes relative to the unbound state occur, but these events are not sufficient for signalling. Ligand-complexed receptors, however, form internal tunnels that posit an explanation for how SL exits its receptor after hydrolysis.
Structural analysis of a hormone-bound Striga strigolactone receptor.,Arellano-Saab A, Skarina T, Xu Z, McErlean CSP, Savchenko A, Lumba S, Stogios PJ, McCourt P Nat Plants. 2023 Jun 1. doi: 10.1038/s41477-023-01423-y. PMID:37264151[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Arellano-Saab A, Skarina T, Xu Z, McErlean CSP, Savchenko A, Lumba S, Stogios PJ, McCourt P. Structural analysis of a hormone-bound Striga strigolactone receptor. Nat Plants. 2023 Jun 1. PMID:37264151 doi:10.1038/s41477-023-01423-y
