Aldolase

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Fructose 1,6-bisphosphate aldolase tetramer complex with fructose 1,6-bisphosphate, 3mmt|

Additional Resources

For additional information, see: Carbohydrate Metabolism

References

  1. Schurmann M, Sprenger GA. Fructose-6-phosphate aldolase is a novel class I aldolase from Escherichia coli and is related to a novel group of bacterial transaldolases. J Biol Chem. 2001 Apr 6;276(14):11055-61. Epub 2000 Dec 18. PMID:11120740 doi:http://dx.doi.org/10.1074/jbc.M008061200
  2. Salleron L, Magistrelli G, Mary C, Fischer N, Bairoch A, Lane L. DERA is the human deoxyribose phosphate aldolase and is involved in stress response. Biochim Biophys Acta. 2014 Dec;1843(12):2913-25. doi:, 10.1016/j.bbamcr.2014.09.007. Epub 2014 Sep 16. PMID:25229427 doi:http://dx.doi.org/10.1016/j.bbamcr.2014.09.007
  3. Goyer A, Illarionova V, Roje S, Fischer M, Bacher A, Hanson AD. Folate biosynthesis in higher plants. cDNA cloning, heterologous expression, and characterization of dihydroneopterin aldolases. Plant Physiol. 2004 May;135(1):103-11. Epub 2004 Apr 23. PMID:15107504 doi:http://dx.doi.org/10.1104/pp.103.038430
  4. Smith BJ, Lawrence MC, Barbosa JA. Substrate-Assisted Catalysis in Sialic Acid Aldolase. J Org Chem. 1999 Feb 5;64(3):945-949. PMID:11674166
  5. Wang W, Mazurkewich S, Kimber MS, Seah SY. Structural and kinetic characterization of 4-hydroxy-4-methyl-2-oxoglutarate (HMG)/4-carboxy-4-hydroxy-2-oxoadipate (CHA) aldolase: a protocatechuate degradation enzyme evolutionarily convergent with the HpaI and DmpG pyruvate aldolases. J Biol Chem. 2010 Sep 15. PMID:20843800 doi:10.1074/jbc.M110.159509
  6. Powlowski J, Sahlman L, Shingler V. Purification and properties of the physically associated meta-cleavage pathway enzymes 4-hydroxy-2-ketovalerate aldolase and aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600. J Bacteriol. 1993 Jan;175(2):377-85. PMID:8419288
  7. Bell BJ, Watanabe L, Rios-Steiner JL, Tulinsky A, Lebioda L, Arni RK. Structure of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase from Pseudomonas putida. Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1454-8. Epub 2003, Jul 23. PMID:12876349
  8. Zgiby SM, Thomson GJ, Qamar S, Berry A. Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases. Eur J Biochem. 2000 Mar;267(6):1858-68. PMID:10712619
  9. Hall DR, Bond CS, Leonard GA, Watt CI, Berry A, Hunter WN. Structure of tagatose-1,6-bisphosphate aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases. J Biol Chem. 2002 Jun 14;277(24):22018-24. Epub 2002 Apr 8. PMID:11940603 doi:http://dx.doi.org/10.1074/jbc.M202464200
  10. Joerger AC, Gosse C, Fessner WD, Schulz GE. Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis. Biochemistry. 2000 May 23;39(20):6033-41. PMID:10821675
  11. Rea D, Fulop V, Bugg TD, Roper DI. Structure and mechanism of HpcH: a metal ion dependent class II aldolase from the homoprotocatechuate degradation pathway of Escherichia coli. J Mol Biol. 2007 Nov 2;373(4):866-76. Epub 2007 Jun 26. PMID:17881002 doi:10.1016/j.jmb.2007.06.048
  12. Riedel TJ, Johnson LC, Knight J, Hantgan RR, Holmes RP, Lowther WT. Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria. PLoS One. 2011;6(10):e26021. Epub 2011 Oct 6. PMID:21998747 doi:10.1371/journal.pone.0026021
  13. KARASEK MA, GREENBERG DM. Studies on the properties of threonine aldolases. J Biol Chem. 1957 Jul;227(1):191-205. PMID:13449064
  14. 14.0 14.1 14.2 Voet, D, Voet, J, & Pratt, C. (2008). Fundamentals of biochemistry, third edition. Hoboken, NJ: Wiley & Sons, Inc.
  15. Protein: fructose-1,6-bisphosphate aldolase from human (homo sapiens), muscle isozyme. (2009). Retrieved from http://scop.mrc-lmb.cam.ac.uk
  16. 16.0 16.1 16.2 Gefflaut, T., B. Casimir, J. Perie, and M. Willson. "Class I Aldolases: Substrate Specificity, Mechanism, Inhibitors and Structural Aspects." Prog. Biophys. molec. Biol.. 63. (1995): 301-340.
  17. Dalby A, Dauter Z, Littlechild JA. Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications. Protein Sci. 1999 Feb;8(2):291-7. PMID:10048322
  18. 18.0 18.1 Sygusch, J., and Beaudry, D. "Allosteric communication in mammalian muscle aldolase." Biochem. J.. 327. (1997): 717-720.
  19. Paolella, G, Buono, P, Mancini, F P, Izzo, P, and Salvatore, F. "Structure and expression of mouse aldolase genes." Eur. J. Biochem.. 156. (1986): 229-235.
  20. Buono, P, Cassano, S, Alfieri, A, Mancini, A, and Salvatore, F. "Human aldolase C gene expression is regulated by adenosine 30,50-cyclic monophosphate (cAMP) in PC12 cells." Gene. 291. (2002): 115-121.

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