Cyclooxygenase

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Mouse COX-2 tetramer with heme group (PDB code 5cox)

3D Structures of cyclooxygenase

Updated on 23-July-2013

COX I

3n8v, 1prh - sCOX I – sheep
1pth – sCOX I + aspirin
1pge, 1pgf, 1pgg - sCOX I + iodinated anti-inflammatory drug
1cqe, 3kk6 - sCOX I + anti-inflammatory inhibitor
1igx, 1igz - sCOX I + linoleic acid derivative
1u67 - sCOX I (mutant) + fatty acid substrate
2ayl - sCOX I Mn-substituted + anti-inflammatory drug
3n8w - sCOX I (mutant) + anti-inflammatory drug
3n8x, 3n8z, 1eqg - sCOX I + anti-inflammatory drug
3n8y - sCOX I + aspirin + anti-inflammatory drug
2oye, 2oyu, 1ebv, 1eqh, 1ht5, 1ht8, 1q4g - sCOX I + inhibitor
1diy, 1fe2 – sCOX I + arachidonic acid

COX II

5cox - mCOX II]] - mouse
1cx2, 3pgh, 4cox, 6cox - mCOX II + anti-inflammatory inhibitor
1pxx, 3ln1, 3q7d, 3rr3, 3nt1, 3ntb - mCOX II + anti-inflammatory drug
3qmo, 4fm5 - mCOX II (mutant) + inhibitor
3hs5, 3hs6, 3hs7, 3krk, 3mdl, 3olt, 3olu, 3qh0 - mCOX II (mutant) + fatty acid substrate
3ln0, 3mqe, 3ntg - mCOX II + benzopyran inhibitor
1cvu – mCOX II + peptide + arachidonic acid
1ddx – mCOX II + prostaglandin + arachidonic acid
3tzi, 4e1g – mCOX II (mutant) + acrylic acid

Authorship

This page has been constructed and edited by Maria Saiz, Rafael Gonzalez & Eva Garcia, students of the Biomedicine Master of the Universidad Autonoma de Madrid (Spain) under the supervision of Dr. Cristina Murga, as a contribution to the Molecular Pharmacology Course of the doctoral programme in Biosciences.


References

Proteopedia Page Contributors and Editors (what is this?)

Cristina Murga, Michal Harel, David Canner, María Laura Saiz Álvarez, Alexander Berchansky

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