Molecular Playground/Insulin

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One of the CBI Molecules being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst in the Roberts Research Group and on display at the Molecular Playground.

Human insulin chain A (grey) and chain B (green), 3i40

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For additional details see

Insulin Structure & Function
Diabetes & Hypoglycemia
Insulin (Hebrew)
Insulin mo-or-sl (Hebrew).

3D structures of Insulin (Updated on 29-March-2016)


  1. Sonksen P, Sonksen J. Insulin: understanding its action in health and disease. Br J Anaesth. 2000 Jul;85(1):69-79. PMID:10927996
  2. Davidson HW. (Pro)Insulin processing: a historical perspective. Cell Biochem Biophys. 2004;40(3 Suppl):143-58. PMID:15289650
  3. Zakova L, Barth T, Jiracek J, Barthova J, Zorad S. Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain. Biochemistry. 2004 Mar 2;43(8):2323-31. PMID:14979729 doi:

Additional Resources

For additional information, see: Diabetes & Hypoglycemia

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