Centromere protein 3D structure

3D structures of centromere protein

Updated on 22-January-2025

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• Centromere proteins X, S, W, T
  • 4dra, 4e44, 4ne3, 4ne5, 4ne6 – hCENP-X + CENP-S – human
    
  • 4drb, 4e45 – hCENP-X + CENP-S + Fanconi anemia group M protein
    
  • 4ndy, 4ne1 – hCENP-X + CENP-S + DNA
    
  • 3b0b, 7da0, 7da1 – cCENP-X + CENP-S – chicken
    
  • 7da2 – cCENP-X + CENP-S + Fanconi anemia group M protein
    
  • 3b0c, 3b0d – cCENP-T + CENP-W
    
  • 3vza – cCENP-T residues 63-98 (mutant) + Spc24 + Spc25
    
  • 3vh5, 3vh6 – cCENP-X + CENP-S (mutant) + CENP-W + CENP-T C-terminal (mutant)
    
• Inner centromere protein
  • 4af3, 6gr8, 6gr9 – hINCENP residues 835-903 + aurora kinase + inhibitor
    
  • 2qfa, 6yie – hINCENP residues 1-47 + survivin + borealin
    
  • 6yif, 6yih – hINCENP residues 7-57 + survivin + borealin + histone H3
    
  • 2bfx, 4b8l – fINCENP residues 798-840 + aurora kinase – frog
    
  • 2bfy – fINCENP residues 798-840 + aurora kinase + hesperadin
    
  • 2vgp, 2vrx, 3ztx, 4b8m, 5k3y, 5eyk – fINCENP residues 798-840 + aurora kinase + inhibitor
    
  • 2vgo – fINCENP residues 798-840 + aurora kinase + reversine
    
  • 4c2v – fINCENP residues 798-840 + aurora kinase + barasertib
    
  • 4c2w – fINCENP residues 798-840 + aurora kinase + AMPPNP
    
  • 6o2d – fyNCENP subunit CNP3 – fission yeast
    
  • 6oua – yNCENP subunits CTF3 complex – yeast – Cryo EM
    
  • 6nuw – yNCENP CTF19 complex – Cryo EM
    
  • 6oua – yNCENP subunits CTF3+MCM16+MCM22+WIP1+CNN1 – Cryo EM
    
  • 6qle – yNCENP CCAN complex – Cryo EM
    
  • 6qld – yNCENP CCAN-CENP-A complex – Cryo EM
    
  • 6qlf – yNCENP CCAN complex + MASK1 – Cryo EM
    
• Centromere protein A
  • 3nqu – hCENP-A + histone H4
    
  • 3nqj – hCENP-A residues 60-140 + histone H4
    
  • 3r45 – hCENP-A + histone H4 + Holliday junction recognition protein
    
  • 3an2 – hCENP-A + histone H4 + histone H2A + histone H2B + DNA
    
  • 6l49, 6o1d, 6se0, 6seg, 6tem – hCENP-A + histone H4 + histone H2A + histone H2B + DNA – Cryo EM
    
  • 6buz – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + MBP/CENP-N - Cryo EM
    
  • 6eoc, 6e0p – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + scFv – Cryo EM
    
  • 7d20 – hCENP-A + histone H4 + histone H2A + histone H2B + DNA + Set-8 – Cryo EM
    
  • 7bxt – cCENP-A + histone H4 + histone H2A + histone H2B + DNA – Cryo EM
    
  • 7pkn, 7pii, 7qoo, 7r5r, 7r5s, 7r5v, 7u46, 7u47, 7u4d, 7ywx, 7yyh – hCENP in nucleosome – Cryo EM
    
• Centromere protein C
  • 5lsk, 5lsj – hCENP-C + kinetochore mis12
    
  • 6se6, 6see, 6sef – hCENP-C + histones + DNA - Cryo EM
    
  • 6o2k, 6xwu – CENP-C cupin domain – Drosophila melanogaster
    
• Centromere protein B
  • 1bw6 – hCENP-B DNA-binding domain - NMR
    
  • 1ufi – hCENP-B dimerization domain
    
  • 1hlv – hCENP-B DNA-binding domain + DNA
    
• Centromere protein E
  • 1t5c, 6m4i – hCENP-E motor domain 1-339
    
  • 8hfh – hCENP-E motor domain + AMPPNP
    
  • 8owi – hCENP-E corona-targeting domain 2452-2598
    
  • 8whl – hCENP-E 487-548 + CLASP2
    
• Centromere protein I
  • 5z07 – CtCENP-I – Chaetomium thermophilum
    
• Centromere protein J
  • 5itz – hCENP-J + tubulin
    
  • 7q1e, 7q1f – hCENP-J + tubulin + IE5
    
  • 7z0f, 7z0g – hCENP-J 320-397 + tubulin + IIH5
    
• Centromere protein M
  • 4p0t, 4wau – hCENP-M
    
• Centromere protein N
  • 4wau, 6eqt – hCENP-N
    
  • 6c0w – hCENP-N + histone H4 + histone H2A + histone H2B + DNA + CENP-A - Cryo EM
    
  • 6muo, 6mup – hCENP-N + histone H4 + histone H2A + histone H2B + DNA + CENP-C – Cryo EM
    
• Centromere protein 3 (CBF3) or centromere DNA-binding protein complex CBF3
  • 4aco – yCBF3 subunit A
    
  • 2quq, 2veq – yCBF3 subunit B
    
  • 6f07 – yCBF3 subunit B + suppressor of kinetochore protein – Cryo EM
    
  • 6fe8, 7k79 – yCBF3 subunits B,C+ suppressor of kinetochore protein – Cryo EM
    
  • 6gyp, 6gyu – yCBF3 subunits A,B,C + suppressor of kinetochore protein – Cryo EM
    
  • 6gys – yCBF3 subunits A,B,C + suppressor of kinetochore protein + DNA – Cryo EM
    
  • 1nex – yCBF3 subunit D + peptide
    
• Centromere protein A+C
  • 7by0 – cCENP-A + CENP-C + histone H4 + histone H2A + histone H2B + DNA – Cryo EM
    
• Centromere protein I+K+H
  • 5z08, 7pb4 – CtCENP-I + CENP-K + CENP-H
    
• Centromere protein O+P+Q+R+U
  • 7pb8 – hCENP-O + CENP-P + CENP-Q + CENP-R + CENP-U
    
• Centromere proteins C+H+I+K+L+M+N+O+P+Q+S+T+U+W+X or kinetochore
  • 7xho – hKinetochore – Cryo EM
    
  • 7xhn – hKinetochore + DNA – Cryo EM
    
  • 8ow1 – yKinetochore + CENP-A – Cryo EM
    
• Centromere protein mis12
  • 5wwl – fyCENP + kinetochore protein NNF1
    
• Centromere protein mis16
  • 5wjc – fyCENP + EIC1
    
  • 6s29 – fyCENP + mis19
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel