2r42

The Biochemical and Structural Basis for feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism

spinqualitylabelsall models 2r42, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2r42 is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.4Å Ligands: FPS, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease KIME_RAT Note=Mutation in the mevalonate kinase gene causes mevalonicaciduria. Function KIME_RAT May be a regulatory site in cholesterol biosynthetic pathway. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Mevalonate kinase

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