3c98

Revised structure of the munc18a-syntaxin1 complex

spinqualitylabelsall models 3c98, resolution 2.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3c98 is a 2 chain structure with sequence from Rattus norvegicus. This structure supersedes the now removed PDB entry 1dn1. The November 2013 RCSB PDB Molecule of the Month feature on SNARE Proteins by David Goodsell is 10.2210/rcsb_pdb/mom_2013_11. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.601Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function STXB1_RAT May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Syntaxin 3D structures Syntaxin-binding protein

Proteopedia Page Contributors and Editors (what is this?)

OCA