3p7o
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Rat Insulin Degrading Enzyme (Insulysin) E111F mutant with two bound peptides
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Structural highlights
FunctionIDE_RAT Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. See AlsoContents | ||||||||||||||||||
This page was last modified 10:39, 21 February 2024.