3qbt
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Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp
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Structural highlights
FunctionRAB8A_HUMAN May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.[1] [2] See Also
References
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This page was last modified 11:39, 14 March 2024.