3qkr
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Mre11 Rad50 binding domain bound to Rad50
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Structural highlights
FunctionRAD50_PYRFU Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449] See AlsoContents | ||||||||||||||||||||
This page was last modified 11:49, 14 March 2024.