3rsm
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Crystal structure of S108C mutant of PMM/PGM
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Structural highlights
FunctionALGC_PSEAE The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production, an exoproduct correlated with pathogenicity, and for biofilm production.[1] [2] See AlsoReferences
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This page was last modified 12:35, 14 March 2024.