3u81
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Crystal structure of a SAH-bound semi-holo form of rat Catechol-O-methyltransferase
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Structural highlights
FunctionCOMT_RAT Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. See AlsoContents | ||||||||||||||||||||
This page was last modified 10:17, 1 March 2024.