4gab

Human AKR1B10 mutant V301L complexed with NADP+ and fidarestat

spinqualitylabelsall models 4gab, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gab is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.5971Å Ligands: CL, FID, NAP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AK1BA_HUMAN Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. See Also Aldo-keto reductase 3D structures

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