Aldo-keto reductase 3D structures

3D structures of Aldo-keto reductase

Updated on 18-September-2024

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• AKR1B1 or aldose reductase See Aldose Reductase
• AKR1B4
  • 4hbk – AKR1B4 – blood fluke
    
• AKR1B10
  • 4xzm, 4gqg – hAKR1B10 + NADP - human
    
  • 4xzn – hAKR1B10 (mutant) + NADP
    
  • 4jih, 4jii, 4i5x, 5y7n – hAKR1B10 + NADP + inhibitor
    
  • 4ga8, 4gab, 1zua, 5liy, 5lik, 5liu, 5liw, 5lix, 4xzl, 4wev, 4icc, 5m2f – hAKR1B10 (mutant) + NADP + inhibitor
    
  • 4gq0 – hAKR1B10 + NADP + caffeic acid ester
    
• AKR1B14
  • 3o3r – rAKR1B14 + NADP - rat
    
  • 3qkz – rAKR1B14 (mutant) + NADP
    
• AKR1C1 See Hydroxysteroid dehydrogenase 20-alpha HSD
• AKR1C2 or 3-alpha hydroxysteroid dehydrogenase See Hydroxysteroid dehydrogenase 3-alpha HSD
• AKR1C3 See Prostaglandin F synthase
• AKR1C4
  • 2fvl – hAKR1C4 + NADP
    
• AKR1C13 or dihydrodiol dehydrogenase
  • 6m7k – mAKR1C13 + cyclic AMP-AMP-GMP - mouse
    
  • 5uxf – mAKR1C13 + cyclic di-AMP
    
• AKR1C21 or 17-alpha hydroxysteroid dehydrogenase See Hydroxysteroid dehydrogenase 17-alpha HSD
• AKR1D1 or 3-oxo-5-beta-steroid 4-dehydrogenase
  • 3caq, 3buv, 3bv7 – hAKR1D1 + NADP
    
  • 3dop – hAKR1D1 + NADP + 5-beta-dehydrotestosterone
    
  • 3uzy – hAKR1D1 (mutant) + NADP + 5-beta-dehydrotestosterone
    
  • 3bur – hAKR1D1 (mutant) + NADP + testosterone
    
  • 3uzz – hAKR1D1 (mutant) + NADP + 5-delta-androstenedione
    
  • 3cas – hAKR1D1 + NADP + 4-androstenedione
    
  • 3g1r – hAKR1D1 + NADP + finasteride
    
  • 3cav – hAKR1D1 + NADP + 5-beta-pregnan-3,20-dione
    
  • 3cmf – hAKR1D1 + NADP + cortisone
    
  • 3cot – hAKR1D1 + NADP + progesterone
    
• AKR2E4
  • 3wcz – AKR2E4 + NADP – silk moth
    
• AKR4C7
  • 5jh1 – maAKR4C7 - maize
    
  • 5jh2 – maAKR4C7 + ADP
    
• AKR4C8
  • 3h7r – AtAKR4C8 + NADP – Arabidopsis thaliana
    
• AKR4C9
  • 3h7u – AtAKR4C9 + NADP
    
• AKR4C13 See Aldose Reductase
• AKR4C14
  • 6kbl – AKR4C14 - rice
    
• AKR4C17
  • 7f7j – EcoAKR4C17 – Echinochloa colona<br />
  • 7f7k, 7f7l – EcoAKR4C17 + NADP
    
  • 7w1w – EcoAKR4C17 (mutant) + NADP
    
  • 7f7m – EcoAKR4C17 + NADP + glyphosate
    
• AKR6D1
  • 8hw0 – DeAKR6D1 + NADP - Devosia
    
• AKR7A1 or aflatoxin B1 aldehyde reductase member 3
  • 1gve – AKR7A1 + NADP – rat
    
• AKR7A5 or aflatoxin B1 aldehyde reductase member 2
  • 2c91 – mAKR7A5 + NADP
    
• AKR11A or IOLS protein
  • 1pyf – BsAKR11A – Bacillus subtilis
    
  • 1pz0 – BsAKR11A + NADP
    
• AKR11B or general stress protein 69
  • 1pz1 – BsAKR11B + NADP
    
• AKR11B4
  • 3n2t – AKR11B4 – Gluconobacter oxydans
    
• AKR11C1
  • 1ynp – BhAKR11C1 – Bacillus halodurans
    
  • 1ynq – BhAKR11C1 + NADP
    
• AKR13B2
  • 8hnq – DeAKR13B2 + NADP
    
• AKR14A1
  • 4ast – EcAKR14A1 – Escherichia coli
    
  • 4aub – EcAKR14A1 + NADP
    
• AKR
  • 6pex – AKR – grape
    
  • 4xap – RmAKR – Rhizobium meliloti
    
  • 5c7h – RmAKR + NADP
    
  • 4xk2 – AKR – Polaromonas
    
  • 6cia – KpAKR + NADP – Klebsiella pneumoniae
    
  • 4wgh – AKR (mutant) + NADP
    
  • 3n6q – EcAKR
    
  • 3o0k – AKR – Brucella melitensis
    
  • 2wzt – MsAKR – Mycobacterium smegmatis
    
  • 2wzm – MsAKR + ligand
    
  • 5t79 – AKR + NADP – Salmonella typhimurium
    
  • 5ket – AKR1 + NADP – Coptotermes gestroi
    
  • 6gtm – AKR + PPGPP – Caulobacter vibrioides
    
  • 8xr2, 8xr3 – SxAKR – Streptomyces xinghaiensis
    
  • 8jwk, 8jwn – SxAKR + NADP
    
  • 8jwm – SxAKR + NADP + tylosin
    

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Michal Harel