4m3l

Crystal Structure of the coiled coil domain of MuRF1

spinqualitylabelsall models 4m3l, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4m3l is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: ACT, GOL, MPD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TRI63_HUMAN E3 ubiquitin ligase. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells. See Also Mur ligase Ubiquitin protein ligase 3D structures

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