4mz6

Structure of importin-alpha: dUTPase S11E NLS mutant complex

spinqualitylabelsall models 4mz6, resolution 1.88Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4mz6 is a 3 chain structure with sequence from Homo sapiens and Mus musculus. This structure supersedes the now removed PDB entry 4fds. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.88Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DUT_HUMAN This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. See Also DUTPase 3D structures Importin 3D structures

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