4v7o

Proteasome Activator Complex

spinqualitylabelsall models 4v7o, resolution 3.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4v7o is a 40 chain structure with sequence from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entries 1vsy and 3l5q. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.005Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PSB6_YEAST The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. See Also Proteasome 3D structures

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