4y9j

Crystal Structure of Caenorhabditis elegans ACDH-11 in complex with C11-CoA

spinqualitylabelsall models 4y9j, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4y9j is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.8Å Ligands: FAD, UCC Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ACD11_CAEEL Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat. See Also Acyl-CoA dehydrogenase 3D structures

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