Acyl-CoA dehydrogenase 3D structures

3D structures of Acyl-CoA dehydrogenase

Updated on 11-September-2024

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• Short chain ACDH
  • 7q86, 7y0a, 7y0b - hSCAD + FAD – human
    
  • 8sgs - hSCAD + FAD – Cryo EM
    
  • 2jif, 2vig - hSCAD + CoA persulfide + FAD
    
  • 1jqi - SCAD + acetoacetyl-CoA + FAD – rat
    
  • 2dvl, 2z1q - TtSCAD + FAD – Thermus thermophilus
    
  • 5ol2 – ACDH + FAD + CoA persulfide + electron transfer flavoprotein – Clostridium difficile
    
  • 7p98 – GmACDH + FAD – Geobacter metallireducens
    
  • 7p9a, 7p9x – GmACDH + FAD + cyclohexene-carboxyl CoA
    
• Medium chain ACDH
  • 8sgp - hMCAD + FAD – Cryo EM
    
  • 1egd, 1ege, 4p13 - hMCAD (mutant) + FAD
    
  • 1egc - hMCAD (mutant) + octanoyl-CoA + FAD
    
  • 1t9g - hMCAD + electron transfer flavoprotein + AMP + FAD
    
  • 2a1t - hMCAD + electron transfer flavoprotein (mutant) + AMP + FAD
    
  • 3mdd – pMCAD + FAD – pig
    
  • 3mde - pMCAD + octanoyl-CoA + FAD
    
  • 1udy - pMCAD + thiaoctanoyl-CoA + FAD
    
  • 1ws9, 2cx9 - TtMCAD
    
  • 1ukw, 2d29 - TtMCAD + FAD
    
• Long chain ACDH
  • 8w0t - hLCAD + FAD
    
  • 8w0z - hLCAD + FAD + lauric acid
    
  • 8w0u - hLCAD + FAD + acetoacetyl-CoA
    
• Very long chain ACDH
  • 7s7g - hVLCAD + FAD
    
  • 2uxw - hVLCAD + tetradecanoyl CoA + FAD
    
  • 3b96 - hVLCAD + trans-δ2-palmitenoyl CoA + FAD
    
• Unspecified length ACDH
  • 2oku – ACDH C terminal – Porphyromonas gingivalis
    
  • 2pg0 - ACDH + FAD – Geobacillus kaustophilus
    
  • 2wbi – hACDH 11 + FAD
    
  • 3nf4, 3pfd – ACHD + FAD – Mycobacterium thermoresistibile
    
  • 4x28 - ACHD + FAD – Mycobacterium tuberculosis
    
  • 4m9a – ACDH + FAD – Burkholderia thailandensis
    
  • 3owa - ACDH + FAD – Bacillus anthracis
    
  • 4rm7 – ShACDH – Slackia heliotrinireducens
    
  • 4w9u – ACDH – Brucella abortus
    
  • 5ez3 – ACDH + FAD – Brucella melitensis
    
  • 4y9l – CeACDH + FAD – Caenorhabditis elegans
    
  • 4y9j – CeACDH + FAD + CoA-11
    
  • 5af7 – AmACDH + FAD – Advenella mimigardefordensis
    
  • 5ahs – AmACDH + FAD + succinyl-CoA
    
  • 5lnx – ACDH + FAD – Bacillus subtilis
    
  • 6es9 – ACDH + FAD + CoA – Paracoccus denitrificans
    
  • 4y9l – CeACDH + FAD – Caenorhabditis elegans
    
  • 4y9j – CeACDH + FAD + undecanoyl-CoA
    
  • 6kse – ACDH (mutant) + FAD + stearoyl-CoA – Mycobacterium tuberculosis
    
  • 3oib, 4iv6, 6kpt, 6kri – MsACDH + FAD – Mycobacterium smegmatis
    
  • 6ks9 – MsACDH (mutant) + FAD
    
  • 6ksa – MsACDH (mutant) + FAD + stearoyl-CoA
    
  • 6ksb, 6lpy, 6lq0, 6lq1, 6lq2, 6lq3, 6lq4, 6lq5, 6lq6, 6lq7, 6lq8 – MsACDH (mutant) + FAD + CoA
    
  • 7szv – ACDH + FAD derivative – Mycobacterium marinum
    
  • 7w0j – TfACDH – Thermobifida fusca
    
  • 8i4p – TfACDH + FAD
    
  • 8i4r – TfACDH + FAD + acetyl-CoA
    
  • 8hk0 – ACDH + FAD + dehydrogenase – Streptomyces ficellus
    
• Butyryl-CoA dehydrogenase
  • 4u83 – ShBCDH
    
  • 1buc – BCDH + acetoacetyl-CoA + FAD – Megasphaera elsdenii
    
  • 1rx0 – hiso-BCDH + methacrylyl-CoA + FAD
    
  • 6cy8, 6cxt – BCDH + alpha/beta hydrolase fold protein + FAD – Marinomonas mediterranea
    
• Glutaryl-CoA dehydrogenase
  • 1siq – hGCDH + FAD
    
  • 2r0m, 2r0n – hGCDH (mutant) + FAD
    
  • 1sir – hGCDH + FAD + butyryl-CoA
    
  • 3eom, 3ii9 – BpGCDH – Burkholderia pseudomallei
    
  • 3d6b, 3eon, 3gnc, 3gqt – BpGCDH + inhibitor
    
  • 3sf6, 3swo – MsGCDH + FAD derivative
    
  • 3mpi – DmGCDH + FAD + glutaryl-CoA – Desulfococcus multivorans
    
  • 3mpj – DmGCDH + FAD + peptide
    
• Isovaleryl-CoA dehydrogenase
  • 1ivh – hICDH + FAD + CoA persulfide
    
  • 4o5m – ICDH – Brucella suis
    
  • 4iv6 – MsICDH + FAD derivative
    
• 3-hydroxyacyl-CoA dehydrogenase
  • 8cbm, 8cbo – hHACDH 2 + CCA adding enzyme + tRNA methyltransferase + tRNA-Ile + NAD + CDP + SAH – Cryo EM
    
  • 8cbo – hHACDH 2 + zinc phosphodiesterase+ tRNA methyltransferase + tRNA-Ile + NAD + SAH – Cryo EM
    
  • 8cbk – hHACDH 2 + RNase P + tRNA methyltransferase + tRNA-His + NAD + SAH – Cryo EM
    
  • 7onu – hHACDH 2 + RNase P+ tRNA methyltransferase + tRNA-Tyr + NAD – Cryo EM
    
  • 7n09 – HACDH 2 + NAD – worm
    
  • 7o4u – MtHACDH + NAD
    
  • 7o1j, 7o1m, 7o4q, 8oql – MtHACDH + acyltransferase
    
  • 8opw – MtHACDH + acyltransferase + caffeine
    
  • 8opu, 8opy, 8oqm, 8oqn, 8oqp, 8oqq, 8oqr, 8oqs, 8oqt, 8oqu, 8oqv – MtHACDH + acyltransferase + benzenesulfonic acid derivative
    
  • 7o1i, 7o1l, 7o4r – MtHACDH + acyltransferase + CoA
    
  • 7o4s, 7o4t – MtHACDH + acyltransferase + CoA + ADP
    
  • 8opx – MtHACDH + acyltransferase + trehalose
    
  • 8opv – MtHACDH + acyltransferase + resveratrol
    
  • 7o4v – MtHACDH + acyltransferase + NAD
    
  • 7o1g, 7o1k – MtHACDH (mutant) + acyltransferase
    

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Michal Harel