5fbr

PI4KB in complex with Rab11 and the MI359 Inhibitor

spinqualitylabelsall models 5fbr, resolution 3.28Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fbr is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.28Å Ligands: 5W7, GSP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PI4KB_HUMAN Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity). See Also Phosphatidylinositol 4-kinase Ras-related protein Rab 3D structures

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