5v5i
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OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1
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Structural highlights
FunctionL_CCHFI Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity. See AlsoContents | ||||||||||||||||||||
This page was last modified 09:42, 2 April 2025.