6aw8

2.25A resolution domain swapped dimer structure of SAH bound catechol O-methyltransferase (COMT) from Nannospalax galili

spinqualitylabelsall models 6aw8, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6aw8 is a 3 chain structure with sequence from Nannospalax galili. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.25Å Ligands: CA, SAH Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A452CSQ0_NANGA Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.[ARBA:ARBA00003256] See Also Catechol O-methyltransferase 3D structures

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