6opl
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Human biliverdin IX beta reductase Q14R mutant: NADP complex
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Structural highlights
FunctionBLVRB_HUMAN Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.[1] See AlsoReferences | ||||||||||||||||||||
This page was last modified 07:14, 11 October 2023.