7xme

Structure of Influenza A virus polymerase basic protein 2 (PB2) with an azazindole derivative

spinqualitylabelsall models 7xme, resolution 2.52Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7xme is a 4 chain structure with sequence from Influenza A virus (A/Victoria/3/1975(H3N2)). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.521Å Ligands: GIH, IOD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PB2_I75A3 Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity). See Also RNA polymerase 3D structures

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