Antifreeze protein
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FunctionAntifreeze protein (AFP) permits the survival of certain organisms in subzero temperatures. AFP binds to small ice crystals thus inhibiting their growth.[1]. There are 3 types of AFP which differ in the ice crusts face to which they bind[2].
RelevanceAFPs are added to ice cream and yogurt. AFPs are tested as freeze tolerant for crops, cryosurgery, hypothermia therapy, food preservation and tissue transplant preservation. Structural highlightsAFP flat surface presents Thr residues at distances which match those of the primary prism plane of ice thus allowing for favorable interactions between the protein and ice crystals. Fungal antifreeze protein (PDB code 3vn3)[3] is shown. 3D Structures of antifreeze proteinAntifreeze protein 3D structures
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This page was last modified 08:40, 22 June 2026.