Gag polyprotein 3D structures

3D structures of Gag polyprotein

Updated on 07-July-2025

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• Gag polyprotein from HIV-1; matrix protein 1-132; capsid protein 133-362
  • 2h3i – Gag matrix protein – HIV-1
    
  • 2h3f, 2h3i, 1uph - Gag matrix protein – NMR
    
  • 7jxr, 7jxs - Gag matrix protein (mutant)
    
  • 2jmg, 2nv3 - Gag matrix protein (mutant) – NMR
    
  • 7ovq - Gag matrix protein – Cryo EM
    
  • 2xde - Gag matrix protein + inhibitor
    
  • 2h3q, 2h3v, 2h3z - Gag matrix protein + phosphatidyl inositol bisphosphate - NMR
    
  • 1gwp - Gag core domain N-terminal 132-283 – NMR
    
  • 4j91, 4j92, 4j93 - Gag core domain N-terminal + inhibitor
    
  • 2x2d - Gag core domain N-terminal + peptidyl-prolyl cis-trans isomerase A
    
  • 1baj – Gag capsid protein 146-229
    
  • 7r7q – Gag capsid protein 278-377 - NMR
    
  • 7r7p – Gag capsid protein 278-377 + IHP - NMR
    
  • 5teo - Gag capsid protein C-terminal
    
  • 4coc, 4cop,6n3j - Gag capsid protein C-terminal (mutant)
    
  • 6n3u, 7mkc - Gag capsid protein C-terminal (mutant) + inhibitor
    
  • 6b2g, 6b2h, 6b2i, 6b2j, 6b2k, 6mqa, 6mqo, 6mqp, 6obh, 6r6q, 6r8c - Gag capsid protein
    
  • 6x63 - Gag capsid protein - NMR
    
  • 5upw, 5mcy, 5mcx, 6skm, 6skn, 6slq, 6slu, 6smu, 6vws, 6wap, 8ckv, 8ckw, 8ckx, 8cky, 8ckz, 9d88, 9h1p - Gag capsid protein – Cryo EM
    
  • 2lf4, 6axr, 6axs, 6axt, 6axv, 6axw, 6axx, 6axy, 6omt, 7mn0, 7qdf - Gag capsid protein (mutant)
    
  • 7urt, 8eep, 8eet - Gag capsid protein (mutant) – Cryo EM
    
  • 4u0d, 6ay9, 6aya - Gag capsid protein + peptide
    
  • 6ern - Gag capsid protein + ATP
    
  • 6erm - Gag capsid protein + TTP derivative
    
  • 6h09, 6es8 - Gag capsid protein + IHP
    
  • 6pu1, 8cl3, 8cl4 - Gag capsid protein + SEC24C peptide
    
  • 8cl1, 8cl2 - Gag capsid protein + CPSF6 peptide – Cryo EM
    
  • 8gdv - Gag capsid protein (mutant) + CPSF6 peptide + IP6
    
  • 8cl0 - Gag capsid protein + nup153 peptide – Cryo EM
    
  • 8tqp - Gag capsid protein + inhibitor
    
  • 9d6d, 9d6e - Gag capsid protein (mutant) + inhibitor – Cryo EM
    
  • 2xt1 – Gag C terminal + camelid VHH
    
  • 6bhr, 6bhs, 6bht - Gag capsid p24 (mutant) + IHP
    
  • 6v2f - Gag capsid p24 + pyridine derivative
    
  • 6vkv - Gag capsid p24 (mutant) + pyridine derivative
    
  • 5mdg, 5mdf, 5mde, 5mdd, 5mdc, 5mdb, 5mda, 5md9, 5md8, 5md7, 5md6, 5md5, 5md4, 5md3, 5md2, 5md1, 5md0, 5mcz, 6ec2 - Gag capsid p24 – Cryo EM
    
  • 1l6n - Gag N-terminal 1-283 – NMR
    
  • 6rwg - Gag residues 271-427 (mutant) – NMR
    
  • 1u57 - Gag residues 345-392 – NMR
    
  • 1esk - Gag NCPT 12-53 – NMR
    
  • 2znf – Gag zinc fingerlike domain 389-406 – NMR
    
  • 1fgl – Gag residues 81-105 + cyclophilin A
    
• Gag polyprotein from HIV-2
  • 2wlv - Gag residues 99-242 – HIV-2
    
  • 2ec7 – Gag – NMR
    
  • 8w52 – Gag matrix protein
    
• Gag polyprotein from Rous sarcoma virus
  • 3g0v, 3g1g, 3g21, 3g1i - Gag C terminal 389-465 – Rous sarcoma virus
    
  • 3g26, 3g28, 3g29 - Gag C terminal (mutant)
    
  • 1eoq - Gag C terminal – NMR
    
  • 1p7n – Gag N terminal215-386
    
  • 1em9 - Gag N terminal – NMR
    
  • 1a6s – Gag M domain (mutant) 2-87 - NMR
    
  • 5a9e - Gag residues 84-577 – Cryo EM
    
  • 6ccj - Gag matrix protein – NMR
    
  • 6ce5, 6cus, 6cv8, 6cw4 - Gag matrix protein + phosphate derivative – NMR
    
  • 7no0, 7no1, 7no2, 7no3, 7no4, 7no5, 7no6, 7no7, 7no9, 7noa, 7nob, 7noc, 7nod, 7noe, 7nof, 7nog, 7noh, 7noi, 7noj, 7nok, 7nol, 7nom, 7non, 7noo, 7nop, 7noq - Gag capsid protein p27 – Cryo EM
    
• Gag polyprotein from Simian immunodeficiency virus
  • 1ecw, 1ed1 - Gag
    
• Gag polyprotein from feline immunodeficiency virus
  • 4ic9 – Gag matrix protein
    
  • 6wa3, 6wa4, 6wa5 – Gag matrix protein – NMR
    
• Gag polyprotein from Moloney murine leukemia virus
  • 1u7k, 3bp9 - Gag residues 215-345
    
  • 6hwy - Gag residues 215-450 – Cryo EM
    
  • 6gza - Gag residues 346-432
    
  • 1u6p – Gag residues 479-534 + DNA
    
  • 6mig - Gag residues 683-937 + DNA
    
• Gag polyprotein from human T-cell leukemia virus
  • 8pug, 8puh – Gag – Cryo EM
    
• Gag polyprotein from mouse mammary tumor virus
  • 5hyb - Gag residues 2-92 (mutant)
    
• Gag polyprotein from equine infectious anemia virus
  • 1hek – Gag
    
  • 6t61, 6t63, 6t64 – Gag – Cryo EM
    
• Gag polyprotein from Mason-Pfizer monkey virus
  • 1cl4 - Gag residues 49-80 (mutant) – NMR
    
  • 6hwi – Gag 317-516 – Cryo EM
    
• Gag polyprotein from human spumaretrovirus
  • 4jnh - Gag N terminal 1-179
    
  • 4jmr - Gag N terminal + Env protein
    
  • 5m1h, 5m1g - Gag residues 300-477 - NMR
    
• Gag polyprotein from human endogenous retrovirus
  • 6ssj, 6ssk, 6ssl, 6ssm - Gag capsid protein – Cryo EM
    
  • 6sai - Gag C-terminal 198-288 – NMR
    
• Gag polyprotein from chimpanzee simian foamy virus
  • 8ozk, 8ozl, 8ozm, 8ozn - Gag capsid protein – Cryo EM
    

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Michal Harel