User contributions for Mayank Mamgaain
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Results for Mayank Mamgaain talk block log uploads logs
A user with 32 edits. Account created on 3 September 2020.
15 September 2020
- 07:2307:23, 15 September 2020 diff hist −31,516 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
9 September 2020
- 10:0210:02, 9 September 2020 diff hist +17,221 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 09:3209:32, 9 September 2020 diff hist +343 N File:Iub2359-sup-0002-figures2.jpg Superimposition of the Cryo‐EM structure of SCV2‐nsp12:RNA and the model of the ternary complex. The backbone of the Cryo‐EM structure is colored green and that of the model is colored cyan. The RNA is shown in the stick representation. The incorpor current
- 09:2909:29, 9 September 2020 diff hist +486 N File:Iub2359-sup-0001-figures1.jpg Model of the functional ternary complex of the SCV2‐nsp12 enzyme in the complex. The RNA substrate and incoming GTP are shown in stick representation and colored according to element. The N‐terminal extension region and the palm, fingers, and thumb do current
- 09:0209:02, 9 September 2020 diff hist +627 N File:Figure 5.jpg Binding site of methylcobalamin (MeCo) overlaps with that of incoming nucleotide. The Cryo‐EM structure of SCV2‐nsp12 in complex with RNA bearing remdesivir monophosphate (RMP) at the 3′ end of the primer (7BV2) and the model of the SCV2‐nsp12:met current
- 07:5407:54, 9 September 2020 diff hist 0 File:Figure 4B.jpg uploaded a new version of "Image:Figure 4B.jpg": Residues of SCV2‐nsp12 that interact with methylcobalamin. The LigPlot representation of the interacting residues is displayed here. The polar interactions are shown in the form of dotted lines and th current
- 07:5207:52, 9 September 2020 diff hist 0 File:Figure 4B.jpg uploaded a new version of "Image:Figure 4B.jpg": Residues of SCV2‐nsp12 that interact with methylcobalamin. The LigPlot representation of the interacting residues is displayed here. The polar interactions are shown in the form of dotted lines and th
- 07:4807:48, 9 September 2020 diff hist +286 N File:Figure 4B.jpg Residues of SCV2‐nsp12 that interact with methylcobalamin. The LigPlot representation of the interacting residues is displayed here. The polar interactions are shown in the form of dotted lines and the residues involved in hydrophobic interactions are h
- 07:2207:22, 9 September 2020 diff hist +387 N File:Figure 4A.jpg Residues of SCV2‐nsp12 that interact with methylcobalamin. The vitamin B12 (MeCo) molecule is shown in stick representation and colored according to element. The N‐terminal extension region and the palm, fingers, and thumb domains are shown in green, current
- 06:2806:28, 9 September 2020 diff hist 0 N File:Figure 1a.jpg No edit summary current
- 06:2506:25, 9 September 2020 diff hist 0 File:Figure 1.jpg uploaded a new version of "Image:Figure 1.jpg" current
- 06:2306:23, 9 September 2020 diff hist +223 N File:SCV2‐nsp12.jpg Alignment of the sequence of SCV2‐nsp12 (119–901) with the sequence of the available structure of SARS‐nsp12 (6NUR). The SCV2‐nsp12 sequence exhibits about 97% identity with the corresponding stretch in SARS‐nsp12 current
- 06:1306:13, 9 September 2020 diff hist 0 File:Figure 3.jpg uploaded a new version of "Image:Figure 3.jpg": Model of the SCV2‐nsp12 enzyme in complex with methylcobalamin. The vitamin B12 molecule is shown in stick representation and colored according to element. The N‐terminal extension region and the pal current
- 05:3305:33, 9 September 2020 diff hist 0 File:Figure 3.jpg uploaded a new version of "Image:Figure 3.jpg": Model of the SCV2‐nsp12 enzyme in complex with methylcobalamin. The vitamin B12 molecule is shown in stick representation and colored according to element. The N‐terminal extension region and the pal
- 05:3205:32, 9 September 2020 diff hist 0 File:Figure 3.jpg uploaded a new version of "Image:Figure 3.jpg": Model of the SCV2‐nsp12 enzyme in complex with methylcobalamin. The vitamin B12 molecule is shown in stick representation and colored according to element. The N‐terminal extension region and the pal
- 05:0605:06, 9 September 2020 diff hist +409 N File:Figure 3.jpg Model of the SCV2‐nsp12 enzyme in complex with methylcobalamin. The vitamin B12 molecule is shown in stick representation and colored according to element. The N‐terminal extension region and the palm, fingers, and thumb domains are shown in green, cy
7 September 2020
- 10:0810:08, 7 September 2020 diff hist −40 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 10:0510:05, 7 September 2020 diff hist −53 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 10:0210:02, 7 September 2020 diff hist +16 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 09:3509:35, 7 September 2020 diff hist +301 N File:DeepakTNair PAC2020 Figure3.jpg Model of the SCV2‐nsp12 enzyme in its apostate. The N‐terminal extension region and the palm, fingers, and thumb domains are shown in green, cyan, yellow, and orange, respectively. The catalytic residues Asp618, Asp760, and Asp761 are colored accordin current
- 09:3409:34, 7 September 2020 diff hist −548 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 09:1909:19, 7 September 2020 diff hist +45 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 09:1509:15, 7 September 2020 diff hist 0 File:Iub2359-fig-0001-m.jpg uploaded a new version of "Image:Iub2359-fig-0001-m.jpg" current
- 09:1409:14, 7 September 2020 diff hist +331 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 09:0809:08, 7 September 2020 diff hist +6 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 09:0509:05, 7 September 2020 diff hist −4 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:3406:34, 7 September 2020 diff hist +17 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:3206:32, 7 September 2020 diff hist +235 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:2506:25, 7 September 2020 diff hist 0 N File:Iub2359-fig-0001-m.jpg No edit summary
- 06:2306:23, 7 September 2020 diff hist −77 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:1906:19, 7 September 2020 diff hist +2,838 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:0606:06, 7 September 2020 diff hist −4 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:0506:05, 7 September 2020 diff hist +486 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 06:0006:00, 7 September 2020 diff hist −3 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 05:5705:57, 7 September 2020 diff hist +43 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 05:5505:55, 7 September 2020 diff hist +6 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 05:5505:55, 7 September 2020 diff hist +33 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 05:4105:41, 7 September 2020 diff hist +7,093 Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi No edit summary
- 05:3405:34, 7 September 2020 diff hist +5,582 N Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 vi New page: '''Abstract''' SARS‐CoV‐2 is the causative agent for the ongoing COVID19 pandemic, and this virus belongs to the Coronaviridae family. Like other members of this family, the virus pos...
