Transthyretin 3D structures

3D structures of transthyretin

Updated on 23-January-2024 - For a general description of the protein see Transthyretin

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• Transthyretin
  • 2pab, 1tta, 1ttb, 1etb, 1bmz, 1f41, 1dvq, 1fh2, 1qwh, 1zcr, 1zd6, 2h4e, 2qgb, 3cbr, 3d7p, 3cfm, 3i9p, 3a4d, 3a4e, 3a4f, 3ssg, 3u2i, 3w3b, 4mrb, 4pvl, 4pvn, 4tlt, 5k1j, 5k1n, 5cn3, 5cnh, 5dwp, 5lll, 5n7c, 5n62, 5n5q, 7q3i, 8awi – hTTR – human
    
  • 3u2j, 4pvm – hTTR - neutron
    
  • 1eta, 1ttc, 1tsh, 1bzd, 1bze, 1fhn, 1g1o, 1x7s, 2qel, 2trh, 2try, 3dgd, 3did, 3kgs, 3tfb – hTTR (amyloidogenic mutant)
    
  • 7ob4, 8e7d - hTTR – Cryo EM
    
  • 6sdz, 8ade, 8e7e, 8e7h, 8e7i, 8e7j, 8pke, 8pkf, 8pkg, 8tdn, 8tdo - hTTR (amyloidogenic mutant) – Cryo EM
    
  • 1ttr – hTTR (cardiomyapatic mutant)
  • 1bz8, 5ttr, 1f86, 1gko, 1iii, 1iik, 1ijn, 1sok, 1soq, 1x7t, 2g3x, 2g3z, 2g4e, 2g4g, 2noy, 3bt0, 3cxf, 3djr, 3djs, 3djt, 3djz, 3dk0, 3dk2, 3do4, 3gps, 3grb, 3grg, 3i9a, 3i9i, 4mrc, 4pwe, 5dej, 5clx, 5clx, 5clz, 5cm1, 4tlu, 4tnf, 4tng, 4tkw, 4tl4, 4tl5, 4tlk, 4tls, 4tm9, 4tne, 5llv, 5h0z, 5h0y, 5h0x, 5h0w, 5h0v, 5fw8, 5fw7, 5fw6, 5fo2, 5cly, 6fzl, 6fxu, 6fwd, 6e71, 6e75, 6e76, 5oq0, 5nfw, 5nfe, 6kgb, 7tha, 7wl6, 7y1i, 7y6j, 8hy4, 8i00, 8i0o, 8t5x – hTTR (mutant)
    
  • 2nbp, 2nbo – hTTR (mutant) – NMR
    
  • 7rlk – TTR – wallaby
    
  • 2qpf – TTR - mouse
  • 1gke – rTTR – rat
    
  • 1tfp – TTR – chicken
    
  • 1oo2, 1sn2 – sbTTR – sea bream
    
  • 3uaf – TTR-52 (mutant) – Caenorhabditis elegans
    
• Transthyretin binary complexes
  • 1thc, 2h1x, 2h6u – hTTR + hydroxyaurone derivative
    
  • 4pm1 - hTTR + estradiol derivative
    
  • 1tlm – hTTR + milrinone
  • 1bm7, 3ozl – hTTR + flufenamic acid
  • 1dvs, 1dvt, 1dvu, 1dvx, 1dvy, 1dvz, 1tt6, 1tz8, 2f8i, 2fbr, 2flm, 2g5u, 2g9k, 2gab, 2qgc, 2qgd, 2qge, 3cn0, 3cn1, 3cn2, 3cn3, 3cn4, 3esn, 3eso, 3esp, 3glz, 3gs0, 3gs4, 3gs7, 3imr, 3ims, 3imt, 3imu, 3imv, 3imw, 3ipb, 3ipe, 3m10, 2fbr, 2flm, 3m1o, 3tct, 4fi7, 4fi8, 4fi6, 5tzl, 6e6z – hTTR + amyloid disease inhibitor
    
  • 4his, 4hiq, 6imx, 6imy, 6e72, 6e74, 6e77 - hTTR (mutant) + amyloid disease inhibitor
    
  • 6fft - hTTR (mutant) + amyloid disease inhibitor - Neutron
    
  • 4abq, 4abv, 4abw, 4ac2, 4ac4, 4act, 4ank, 4abu – hTTR + ligand
    
  • 4des, 4det, 4der, 4dew, 4deu – hTTR + flavonoid
    
  • 6u0q, 7erh, 7q9l, 7q9n, 7qc5, 8dw5, 8hej, 8w48 – hTTR + inhibitor
    
  • 7erh – hTTR + inhibitor
    
  • 1u21, 3cfn, 3cfq, 3cft, 3hj0, 3nee, 3neo, 3p3r, 3p3s, 3p3t, 3p3u, 4ky2, 4mas, 5e23, 5e4a, 5e4o, 5ezp, 5ayt, 4ydm, 4ydn, 4tq8, 4tqh, 4tqi, 4tqp, 5jim, 5jid, 6gr7, 6grp, 6ep1, 5u4g, 6tjn, 6ti9 – hTTR + inhibitor
    
  • 3nes, 3nex, 7dt3, 7dt5, 7dt6, 7dt8, 7ejq, 7ejr, 7erj, 7eri, 8ii1, 8ii2, 8ii3, 8ii4, 8w43 – hTTR (mutant) + inhibitor
    
  • 1e3f, 1e4h, 1e5a, 2b15, 5hjg, 5l4j – hTTR + phenol derivative
    
  • 4l1s - hTTR + benzamide derivative
    
  • 4l1t - hTTR + benzoate derivative
    
  • 5jiq - hTTR + benzophenone derivative
    
  • 5l4m, 6grp - hTTR + pyridine derivative
    
  • 4n85, 4n86 - hTTR + glabridin
    
  • 4n87 - hTTR (mutant) + glabridin
    
  • 2b14, 2b16 – hTTR (mutant) + phenol derivative
    
  • 6r66, 6r67, 6r68 - hTTR + flurbiprofen analog
    
  • 6r6i - hTTR (mutant) + flurbiprofen analog
    
  • 3kgt, 3kgu, 5akv – hTTR (mutant) + genistein derivative
  • 3ng5 – hTTR (mutant) + epigallocatechin gallate
  • 1tyr – hTTR + retinoic acid
  • 1z7j - hTTR + tetraiodotyroacetic acid
  • 1y1d, 2b77, 2b9a, 3d2t, 3fc8, 3fcb, 2f7i, 4ikl, 4ikk, 4ikl, 4iki, 4ik7, 4ik6, 4iiz, 4ikj, 5l4i, 6e70, 6d0w – hTTR + NSAID drug
    
  • 4i89, 6e78, 6e73, 7erk, 7ycq - hTTR (mutant) + NSAID drug
    
  • 8aww, 8ig1 - hTTR + non-NSAID drug
    
  • 4i87, 4i85 - hTTR (mutant) + fibrillogenesis inhibitor
    
  • 3b56 – hTTR + salicylic acid derivative
    
  • 4hjs, 4hjt, 4hju – hTTR + covalent kinetic stabilizer
    
  • 4pmf - hTTR + curcumin
    
  • 4qxv, 5en3, 5ihh - hTTR + luteolin
    
  • 4qya - hTTR (mutant) + luteolin
    
  • 4pwf - hTTR (mutant) + ferulic esterase
    
  • 4pwg, 4pwh, 4qrf - hTTR (mutant) + caffeic esterase
    
  • 4pwi - hTTR (mutant) + rosamariic acid
    
  • 4pwj, 4pwk - hTTR (mutant) + propolis
    
  • 4d7b, 6suh, 6sug, 8c85, 8c86 - hTTR + tolcapone analog
    
  • 5a6i, 6xtk, 6txw, 6txv, 7ybr - hTTR (mutant) + tolcapone
    
  • 5aks, 5akt, 5al0, 7q9o - hTTR + resveratrol
    
  • 8w42, 8w44 - hTTR (mutant) + resveratol
    
  • 5al8 - hTTR + daidzein glucuronide
    
  • 4y9b, 4y9c, 4y9e, 4y9f, 4y9g - hTTR (mutant) + mangostin
    
  • 4wnj, 7z60 - hTTR + quercetin derivative
    
  • 5l4f - hTTR + cresol derivative
    
  • 4wns, 5u48, 5u49, 5u4a, 5u4b, 5u4c, 5u4d, 5u4e, 5u4f 5u4g - hTTR + stilbene derivative
    
  • 8w45, 8w46 - hTTR (mutant) + stilbene derivative
    
  • 4wo0 - hTTR + apigenin
    
  • 8w47 - hTTR (mutant) + isorhapontigenin
    
  • 7w9q, 7w9r - hTTR (mutant) + naringenin derivative
    
  • 5boj - hTTR + gemfibrozil
    
  • 7acu - hTTR + benzbromarone
    
  • 1kgi – rTTR + tetraiodotyroacetic acid
    
  • 1kgj – rTTR + dibromoflavone
    
  • 6gnm - sbTTR + benzophenone derivative
    
  • 6gno, 6gnw - sbTTR + phenol derivative
    
  • 6gnp, 6gnr - sbTTR + pyridine derivative
    
  • 6gon, 6goo - sbTTR + perfluorooctanoate
    
  • 6gnw, 6gno, 6gnp, 6gnr, 6gnm, 6gon, 6goo - sbTTR + inhibitor
    
• Transthyretin ternary complexes
  • 4pme - hTTR + ferulic acid + curcumin
    
  • 5cr1- hTTR + resveratrol + T4
    
• Transthyretin complexes with retinol-binding protein
  • 1rlb, 1qab – hTTR + RBP
  • 2wqa – hTTR + RBP + oleic acid
  • 3bsz – hTTR + RBP + antibody
• Transthyretin complexes with thyroxine
  • 2rox, 1ict – hTTR + T4
  • 3ozk – hTTR (mutant) + T4
  • 1tha, 2roy – hTTR + T4 derivative
  • 1ie4 – rTTR + T4
  • 1sn0 – sbTTR + T4
  • 1sn5 – sbTTR + T4 derivative
• Transthyretin peptide amyloid forming
  • 6c3f, 6c3g, 6c3s, 6c3t, 6c4o, 6c88, 4xfn, 4xfo - hTTR
    

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Michal Harel