3rsm: Difference between revisions
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< | ==Crystal structure of S108C mutant of PMM/PGM== | ||
<StructureSection load='3rsm' size='340' side='right'caption='[[3rsm]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3rsm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RSM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
--> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rsm OCA], [https://pdbe.org/3rsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rsm RCSB], [https://www.ebi.ac.uk/pdbsum/3rsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rsm ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ALGC_PSEAE ALGC_PSEAE] The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production, an exoproduct correlated with pathogenicity, and for biofilm production.<ref>PMID:7515870</ref> <ref>PMID:10481091</ref> | |||
== | ==See Also== | ||
*[[Phosphomannomutase|Phosphomannomutase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[ | |||
== | |||
< | |||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Akella | [[Category: Akella A]] | ||
[[Category: Anbanandam | [[Category: Anbanandam A]] | ||
[[Category: Beamer | [[Category: Beamer L]] | ||
[[Category: Kelm A]] | |||
[[Category: Kelm | [[Category: Mehra-Chaudhary R]] | ||
[[Category: Mehra-Chaudhary | [[Category: Van Doren S]] | ||
[[Category: | [[Category: Wei Y]] | ||
[[Category: | |||
Latest revision as of 12:35, 14 March 2024
Crystal structure of S108C mutant of PMM/PGM
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