Interleukin receptor 3D structures: Difference between revisions
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Michal Harel (talk | contribs) New page: ==3D structures of interleukin receptor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Interleukin receptor ... |
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*'''Interleukin receptor type I''' | *'''Interleukin receptor type I''' | ||
*Interleukin-1 receptor | |||
**[[4gaf]] – hIL1R + EBI-005 - human<br /> | |||
**[[1g0y]] – hIL1R + peptide<br /> | |||
**[[4dep]] - hIL1R + hIL1 β + IL1 receptor accessory protein<br /> | |||
*Interleukin-2 receptor | *Interleukin-2 receptor | ||
**[[1z92]] – hIL2R α subunit + IL2 | **[[1z92]] – hIL2R α subunit + IL2<br /> | ||
**[[5m5e]] - hIL2R β | **[[3iu3]], [[3nfp]] - hIL2R α subunit + antibody | ||
**[[5m5e]] - hIL2R β + gamma subunits + IL2 <br /> | |||
**[[2b5i]] - hIL2R α+β+γ subunits + IL2<br /> | **[[2b5i]] - hIL2R α+β+γ subunits + IL2<br /> | ||
**[[3qaz]], [[6dg5]] - hIL2R β+γ subunits + IL2<br /> | **[[3qaz]], [[6dg5]] - hIL2R β+γ subunits + IL2<br /> | ||
**[[2erj]] - hIL2R α (mutant)+β+γ (mutant) subunits + IL2 (mutant)<br /> | **[[2erj]] - hIL2R α (mutant)+β+γ (mutant) subunits + IL2 (mutant)<br /> | ||
**[[3qb7]] - hIL2R γ (mutant) subunit + IL2<br /> | **[[3qb7]] - hIL2R γ (mutant) subunit + IL2<br /> | ||
**[[ | **[[8epa]], [[9jqt]] - hIL2R γ subunit + antibody – Cryo EM<br /> | ||
*Interleukin-3 receptor | *Interleukin-3 receptor | ||
**[[4jzj]] – hIL3R α subunit + antibody<br /> | **[[4jzj]] – hIL3R α subunit + antibody<br /> | ||
**[[5uv8]], [[5uwc]] – hIL3R α subunit (mutant) + IL3<br /> | **[[5uv8]], [[5uwc]] – hIL3R α subunit (mutant) + IL3<br /> | ||
**[[6nmy]] – hIL3R α subunit (mutant) + beta subunit + IL3 + cytokine receptor common subunit b<br /> | |||
**[[4qqv]] - mIL6R β subunit (mutant) - mouse<br /> | |||
*Interleukin-4 receptor | *Interleukin-4 receptor | ||
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**[[3bpn]] - hIL4R α subunit + hIL13R α subunit + IL4<br /> | **[[3bpn]] - hIL4R α subunit + hIL13R α subunit + IL4<br /> | ||
**[[3bpo]] - hIL4R α subunit + hIL13R α subunit + IL13<br /> | **[[3bpo]] - hIL4R α subunit + hIL13R α subunit + IL13<br /> | ||
**[[6oel]] - hIL4R α subunit + hIL2R | **[[8k4q]], [[8z8l]] - hIL4R α subunit + nanobody<br /> | ||
**[[6oel]] - hIL4R α subunit + hIL2R gamma subunit + IL4 + antibody<br /> | |||
*Interleukin-5 receptor | *Interleukin-5 receptor | ||
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**[[3va2]] - hIL5R α subunit + IL5<br /> | **[[3va2]] - hIL5R α subunit + IL5<br /> | ||
**[[6h41]] - hIL5R α subunit + peptide ihibitor<br /> | **[[6h41]] - hIL5R α subunit + peptide ihibitor<br /> | ||
**[[8tld]] - hIL5R α + beta subunits + IL5 – Cryo EM <BR /> | |||
*Interleukin-6 receptor or gp130 | *Interleukin-6 receptor or gp130 | ||
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**[[1i1r]] – hIL6R β subunit + IL6 homolog<br /> | **[[1i1r]] – hIL6R β subunit + IL6 homolog<br /> | ||
**[[1pvh]] - hIL6R β subunit + leukemia inhILbitory factor<br /> | **[[1pvh]] - hIL6R β subunit + leukemia inhILbitory factor<br /> | ||
**[[3l5i]], [[3l5j]], [[3l5h]] - hIL6R β subunit<br /> | **[[3l5i]], [[3l5j]], [[3l5h]] - hIL6R β subunit<br /> | ||
**[[1n26]] - hIL6R α subunit<br /> | **[[1n26]] - hIL6R α subunit<br /> | ||
**[[2arw]] - hIL6R α subunit - NMR<br /> | **[[2arw]] - hIL6R α subunit - NMR<br /> | ||
**[[1p9m]] - hIL6R α + β subunits + IL6 | **[[1p9m]] - hIL6R α + β subunits + IL6<br /> | ||
**[[8upa]] – hIL6R β 124-321 + sIL-6 1-56 – synthetic<br /> | |||
**[[7dc8]] – hIL6R α subunit + antibody<br /> | |||
**[[8iow]], [[8j6f]] – hIL6R α subunit + antibody – Cryo EM<br /> | |||
**[[8d7r]] – hIL6R beta subunit in CLCF1 complex – Cryo EM<br /> | |||
**[[8d74]] – hIL6R beta subunit in CNTF signaling complex – Cryo EM<br /> | |||
**[[8v2b]], [[8v2c]] – hIL6R beta subunit + oncostatin + oncostatin-specific receptor beta subunit – Cryo EM<br /> | |||
**[[8v2a]] – hIL6R beta subunit + oncostatin + LIFR - Cryo EM<br /> | |||
**[[8d6a]] – hIL6R beta subunit + LIF + LIFR - Cryo EM<br /> | |||
**[[5fuc]] - mI6R α subunit + IL6 +VHH6<br /> | |||
**[[2hmh]] - mI6R β subunit + suppressor of cytokine signaling 3<br /> | |||
**[[4gl9]] - mI6R β subunit + suppressor of cytokine signaling 3 + tyrosine-protein kinase<br /> | |||
*Interleukin-7 receptor | *Interleukin-7 receptor | ||
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**[[3up1]] - hIL7R α subunit<br /> | **[[3up1]] - hIL7R α subunit<br /> | ||
**[[3di2]], [[3di3]] – hIL7R α (mutant) subunit + IL7 (mutant)<br /> | **[[3di2]], [[3di3]] – hIL7R α (mutant) subunit + IL7 (mutant)<br /> | ||
**[[6p50]], [[6p67]] - hIL7R α subunit + antibody<br /> | |||
**[[4nn5]], [[4nn6]], [[4nn7]], [[5j12]], [[5j11]] - mIL7R α subunit + thymic stromal lymphopoietin + cytokine receptor-like factor 2<br /> | **[[4nn5]], [[4nn6]], [[4nn7]], [[5j12]], [[5j11]] - mIL7R α subunit + thymic stromal lymphopoietin + cytokine receptor-like factor 2<br /> | ||
**[[8ddc]] – mIL7R alpha subunit transmembrane domain + mIL2R gamma subunit transmembrane domain - NMR<br /> | |||
*Interleukin-9 receptor | |||
**[[8ddd]] – mIL9R transmembrane domain + mIL2R gamma subunit transmembrane domain - NMR<br /> | |||
*Interleukin-10 receptor | *Interleukin-10 receptor | ||
**[[5t5w]] - hIL10 (mutant) + interferon λ receptor 21 + interferon λ-3 subunit <br /> | **[[5t5w]] - hIL10 (mutant) + interferon λ receptor 21 + interferon λ-3 subunit <br /> | ||
*Interleukin-11 receptor | |||
**[[6o4p]] – hIL11R α subunit<br /> | |||
**[[8dpu]] - hIL11R alpha+beta + IL-11<br /> | |||
**[[8dpt]] - hILR11 alpha (mutant) + hILR6 + hIL11– Cryo EM<br /> | |||
*Interleukin-12 receptor | |||
**[[8c7m]], [[8odx]] - hIL13R beta1 subunit FN domains + antibody<br /> | |||
**[[8pb1]], [[8yi7]] - hIL12R α and β + hIL12 α and β – Cryo EM<br /> | |||
**[[8oe0]], [[8xrp]] - hIL12R beta1 and beta2 + hIL12 α and β – Cryo EM<br /> | |||
**[[8oe4]] - hIL12R α and β + hIL12 α and β + hIL23R α and β + hIL23 α and β – Cryo EM<br /> | |||
*Interleukin-13 receptor | *Interleukin-13 receptor | ||
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**[[2ers]] - hIL15R α subunit sushIL domain – NMR<br /> | **[[2ers]] - hIL15R α subunit sushIL domain – NMR<br /> | ||
**[[ | **[[2psm]], [[2z3q]], [[2z3r]] - hIL15R α subunit + IL15<br /> | ||
**[[4gs7]] - hIL15R α subunit + IL15 + hIL2R β,γ subunits<br /> | **[[4gs7]] - hIL15R α subunit + IL15 + hIL2R β,γ subunits<br /> | ||
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**[[5nan]] - hIL17RA + IL17A + IL17F<br /> | **[[5nan]] - hIL17RA + IL17A + IL17F<br /> | ||
**[[4hsa]] - hIL17RA (mutant) + IL17A<br /> | **[[4hsa]] - hIL17RA (mutant) + IL17A<br /> | ||
**[[6hg4]], [[6hg9]] - hIL17RC (mutant) + IL17F<br /> | |||
**[[6hga]] - hIL17RC D2-D4 domains (mutant) + antibody<br /> | |||
**[[3vbc]] – mIL17RB<br /> | **[[3vbc]] – mIL17RB<br /> | ||
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**[[4nzd]] – hIL21R<br /> | **[[4nzd]] – hIL21R<br /> | ||
**[[3tgx]] – hIL21R extracellular domain (mutant) + IL21 | **[[3tgx]] – hIL21R extracellular domain (mutant) + IL21<br /> | ||
**[[7kq7]] – hIL21R + antibody<br /> | |||
**[[9e2t]] - ILR21 + ILR2 gamma + hIL21 (mutant)<BR /> | |||
**[[8ent]] - hIL21R (mutant) + IL2R gamma (mutant) + hIL21 (mutant) <BR /> | |||
*Interleukin-23 receptor | *Interleukin-23 receptor | ||
**[[5mzv]] – hIL23R + IL12 + IL23 + nanobody<br /> | **[[5mzv]] – hIL23R + IL12 + IL23 + nanobody<br /> | ||
**[[9mfg]] – hIL23R + VHH<br /> | |||
*Interleukin-31 receptor | |||
**[[9eza]] – hIL31R D1D2 domain + scFv<br /> | |||
*'''Interleukin receptor type II''' | *'''Interleukin receptor type II''' | ||
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**[[1lqs]], [[1y6m]], [[1y6n]] - hIL10R α (mutant) subunit + IL10 homolog<br /> | **[[1lqs]], [[1y6m]], [[1y6n]] - hIL10R α (mutant) subunit + IL10 homolog<br /> | ||
**[[1y6k ]]- hIL10R α (mutant) subunit + IL10<br /> | **[[1y6k ]]- hIL10R α (mutant) subunit + IL10<br /> | ||
**[[3lqm]] - hIL10R β (mutant) subunit | **[[3lqm]] - hIL10R β (mutant) subunit <br /> | ||
**[[6x93]] - hIL10R + IL10 – Cryo EM<br /> | |||
**[[5t5w]] - hIL10R (mutant) + interferon lambda receptor 1 + interferon lambda-3<br /> | |||
**[[9bpu]], [[9bpv]] - hIL10R + interferon lambda receptor 1 + interferon lambda-3 – Cryo EM<br /> | |||
*Interleukin-20 receptor | *Interleukin-20 receptor | ||
Latest revision as of 07:36, 5 October 2025
3D structures of interleukin receptor
Updated on 05-October-2025
