2vsw: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 2vsw is ON HOLD Authors: MURRAY, J.W., BARR, A., PIKE, A.C.W., ELKINS, J., PHILLIPS, C., WANG, J., SAVITSKY, P., ROOS, A., BISHOP, S., WICKSTROEM, M... |
No edit summary |
||
| (13 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
The | ==The structure of the rhodanese domain of the human dual specificity phosphatase 16== | ||
<StructureSection load='2vsw' size='340' side='right'caption='[[2vsw]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2vsw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsw OCA], [https://pdbe.org/2vsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsw RCSB], [https://www.ebi.ac.uk/pdbsum/2vsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsw ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DUS16_HUMAN DUS16_HUMAN] Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.<ref>PMID:11489891</ref> <ref>PMID:15888437</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vsw_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vsw ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]] | |||
*[[MAP kinase phosphatase|MAP kinase phosphatase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Barr A]] | |||
[[Category: Bishop S]] | |||
[[Category: Bountra C]] | |||
[[Category: Bray J]] | |||
[[Category: Burgess-Brown N]] | |||
[[Category: Edwards AM]] | |||
[[Category: Elkins J]] | |||
[[Category: Gileadi O]] | |||
[[Category: Knapp S]] | |||
[[Category: Murray JW]] | |||
[[Category: Pantic N]] | |||
[[Category: Phillips C]] | |||
[[Category: Pike ACW]] | |||
[[Category: Roos A]] | |||
[[Category: Savitsky P]] | |||
[[Category: Wang J]] | |||
[[Category: Wickstroem M]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 15:31, 13 December 2023
The structure of the rhodanese domain of the human dual specificity phosphatase 16
| ||||||||||||
