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{{STRUCTURE_4nyn|  PDB=4nyn  |  SCENE=  }}
==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1==
===Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1===
<StructureSection load='4nyn' size='340' side='right' caption='[[4nyn]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halsa Halsa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NYN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rnhA, VNG_0255C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=64091 HALSA])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nyn RCSB], [http://www.ebi.ac.uk/pdbsum/4nyn PDBsum]</span></td></tr>
</table>


==Function==
==See Also==
[[http://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA]] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref> 
*[[Ribonuclease|Ribonuclease]]
 
*[[Temp|Temp]]
==About this Structure==
*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
[[4nyn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYN OCA].
__TOC__
 
</StructureSection>
==Reference==
[[Category: Halsa]]
<references group="xtra"/><references/>
[[Category: Ribonuclease H]]
[[Category: Ribonuclease H]]
[[Category: Angkawidjaja, C.]]
[[Category: Angkawidjaja, C]]
[[Category: Kanaya, S.]]
[[Category: Kanaya, S]]
[[Category: Koga, Y.]]
[[Category: Koga, Y]]
[[Category: You, D J.]]
[[Category: You, D J]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Rnase h1]]
[[Category: Rnase h1]]

Revision as of 17:32, 21 December 2014

Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1

4nyn, resolution 1.41Å

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