Serpin: Difference between revisions
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<StructureSection load='3ndd' size='400' side='right' caption='Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry [[3ndd]])' scene=''> | <StructureSection load='3ndd' size='400' side='right' caption='Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry [[3ndd]])' scene=''> | ||
'''Serpin or serine protease inhibitor''' (Ser) are protease inhibitors. | '''Serpin or serine protease inhibitor''' (Ser) are protease inhibitors.<br /> | ||
* Ser E1 is antithrombin. <br /> | |||
* Ser C1 is antithrombin.<br /> | |||
* Ser A5 is protein C inhibitor.<br /> | |||
* Ser A6 is a cortisol-binding globulin. <br /> | |||
* Ser A8 is angiotensinogen. <br /> | |||
* Ser A7 is a thyroxine-binding globulin.<br /> | |||
* Ser B1 is leukocyte elastase inhibitor.<br /> | |||
* Ser B3 is squamos cell carcinoma antigen 1. <br /> | |||
* Ser B5 is Maspin.<br /> | |||
* Ser I1 is neuroserpin. <br /> | |||
* Ser A10 is protein Z-related protease inhibitor. <br /> | |||
* Ser A1 is alpha-1 antitrypsin. <br /> | |||
* Ser A3 is α 1-antichymotrypsin.<br /> | |||
* Ser E1 is plasminogen activator inhibitor 1. | |||
==3D structures of serpin== | ==3D structures of serpin== | ||
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[[Alpha-1-antitrypsin]] | [[Alpha-1-antitrypsin]] | ||
===Ser A3 (α 1-antichymotrypsin)=== | |||
[[2ach]], [[1as4]], [[3caa]] – hSer-A3<br /> | |||
[[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br /> | |||
[[1yxa]] – Ser-A3N - mouse<br /> | |||
===Ser A5=== | ===Ser A5=== | ||
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[[4if8]] – hSer-A12<br /> | [[4if8]] – hSer-A12<br /> | ||
===Ser B1 (leukocyte elastase inhibitor)=== | |||
[[1hle]] – Ser-B1 – horse <br /> | |||
[[4ga7]] – hSer-B1 (mutant) <br /> | |||
===Ser B3=== | ===Ser B3=== | ||
[[2zv6]] – hSer-B3 | [[2zv6]] – hSer-B3 | ||
===Ser B5 (Maspin)=== | |||
[[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br /> | |||
[[1xqj]] – hSer-B5 (mutant) <br /> | |||
===Ser C1=== | ===Ser C1=== | ||
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[[3pzf]] – Ser-2 – malaria mosquito | [[3pzf]] – Ser-2 – malaria mosquito | ||
Revision as of 08:03, 28 July 2014
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