Serpin: Difference between revisions

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<StructureSection load='3ndd' size='400' side='right' caption='Structure of cleaved human serpin A1.  Residues 46-382 (grey), residues 383-418 (green). (PDB entry [[3ndd]])' scene=''>
<StructureSection load='3ndd' size='400' side='right' caption='Structure of cleaved human serpin A1.  Residues 46-382 (grey), residues 383-418 (green). (PDB entry [[3ndd]])' scene=''>


'''Serpin or serine protease inhibitor''' (Ser) are protease inhibitors. Ser E1 is antithrombin. Ser C1 is  antithrombin . Ser A5 is protein C inhibitor. Ser A6 is a cortisol-binding globulin. Ser A8 is angiotensinogen.   Ser A7 is a thyroxine-binding globulin. Ser B3 is squamos cell carcinoma antigen 1. Ser I1 is neuroserpin. Ser A10 is protein Z-related protease inhibitor. Ser A1 is alpha-1 antitrypsin.   Ser E1 is plasminogen activator inhibitor 1.   
'''Serpin or serine protease inhibitor''' (Ser) are protease inhibitors.<br />
* Ser E1 is antithrombin. <br />
* Ser C1 is  antithrombin.<br />
* Ser A5 is protein C inhibitor.<br />
* Ser A6 is a cortisol-binding globulin. <br />
* Ser A8 is angiotensinogen. <br />
* Ser A7 is a thyroxine-binding globulin.<br />
* Ser B1 is leukocyte elastase inhibitor.<br />
* Ser B3 is squamos cell carcinoma antigen 1. <br />
* Ser B5 is Maspin.<br />
* Ser I1 is neuroserpin. <br />
* Ser A10 is protein Z-related protease inhibitor. <br />
* Ser A1 is alpha-1 antitrypsin. <br />
* Ser A3 is α 1-antichymotrypsin.<br />
* Ser E1 is plasminogen activator inhibitor 1.   


==3D structures of serpin==
==3D structures of serpin==
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[[Alpha-1-antitrypsin]]  
[[Alpha-1-antitrypsin]]  
===Ser A3 (α 1-antichymotrypsin)===
[[2ach]], [[1as4]], [[3caa]] – hSer-A3<br />
[[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br />
[[1yxa]] – Ser-A3N - mouse<br />


===Ser A5===
===Ser A5===
Line 47: Line 67:


[[4if8]] – hSer-A12<br />
[[4if8]] – hSer-A12<br />
===Ser B1 (leukocyte elastase inhibitor)===
[[1hle]] – Ser-B1 – horse <br />
[[4ga7]] – hSer-B1 (mutant) <br />


===Ser B3===
===Ser B3===


[[2zv6]] – hSer-B3
[[2zv6]] – hSer-B3
===Ser B5 (Maspin)===
[[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br />
[[1xqj]] – hSer-B5 (mutant) <br />


===Ser C1===
===Ser C1===
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[[3pzf]] – Ser-2 – malaria mosquito
[[3pzf]] – Ser-2 – malaria mosquito


===Maspin===
[[1xqg]], [[1xqj]], [[1wz9]], [[1xu8]] - hMapsin
   
   
   
   

Revision as of 08:03, 28 July 2014

Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry 3ndd)

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky