Dioxygenase 3D structures

3D structures of dioxygenase

Updated on 11-June-2019

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• Dioxygenase Intradiol family
• Protocatechuate 3,4-dioxygenase (PCD)
  • 2pcd, 4who, 4whp – PpPCD α,β + Fe+3 – Pseudomonas putida
    
  • 3pcd, 1ykk, 1ykm, 1yko, 3lkt, 3mfl, 3mi1, 3mv4, 3t63 – PpPCD α,β (mutant) + Fe+3
    
  • 1eo2, 1eo9, 1eoa, 2bum, 2but – AcPCD α,β + Fe+3 - Acinetobacter
    
  • 2bux – AcPCD α,β (mutant) + Fe+3
    
• PCD complex with aromatic compound
  • 3pcf, 3pch, 3pci, 4whq, 4whr, 4whs – PpPCD α,β + Fe+3 + HB derivative
    
  • 3pca, 3pcb, 3pcc – PpPCD α,β + Fe+3 + HB
    
  • 1ykl, 1ykn, 1ykp, 3lmx, 3mv6 – PpPCD α,β (mutant) + Fe+3 + DHB
    
  • 3pcj, 3pck, 3pcl, 3pcm – PpPCD α,β + Fe+3 + hydroxynicotinic acid derivative
    
  • 3pcn, 3pce, 3pcg – PpPCD α,β + Fe+3 + hydroxyphenyl acetate derivative
    
  • 1eob – AcPCD α,β + Fe+3 + DHB
    
  • 2buv, 2bv0 – AcPCD α,β (mutant) + Fe+3 + DHB
    
  • 2bur – AcPCD α,β + Fe+3 + HB
    
  • 2buw – AcPCD α,β (mutant) + Fe+3 + HB
    
  • 1eoc, 2buq – AcPCD α,β + Fe+3 + catechol derivative
    
  • 2buu, 2buy, 2buz – AcPCD α,β (mutant) + Fe+3 + catechol derivative
    
  • 3lxv, 3mi5, 3t67 – PpPCD α,β (mutant) + Fe+3 + catechol derivative
    
• Protocatechuate 4,5-dioxygenase (PCD)
  • 1b4u – SpPCD α,β + Fe+3 + DHB – Sphingomonas paucimobilis
    
  • 1bou – SpPCD α,β + Fe+3
    
• Catechol 1,2-dioxygenase (CTD)
  • 1dlm, 1dlq – AcCTD + Fe+3
    
  • 2azq – PpCTD + Fe+3
    
  • 5umh – CTD – Burkholderia multivorans
    
  • 5td3 – CTD – Burkholderia vietnamiensis
    
  • 5vxt – BaCTD + Fe+3 + catechol – Burkholderia ambifaria
    
• CTD complex with aromatic compound
  • 1dlt, 1dmh – AcCTD + Fe+3 + catechol derivative
    
  • 3hgi – RoCTD + Fe+3 + benzoic acid
    
  • 3hhy, 3hkp – RoCTD + Fe+3 + DHB
    
  • 3hj8, 3hjq, 3hjs, 3i4v, 3i4y, 3i51 – RoCTD + Fe+3 + catechol derivative
    
  • 3hhx – RoCTD + Fe+3 + pyrogallol
    
  • 2xsu – ArCTD + Fe+3 + phosphoinositol derivative – Acinetobacter radioresistens
    
  • 2xsv, 2xsr – ArCTD + Fe+3 + phosphoinositol derivative
    
• Chlorocatechol 1,2-dioxygenase (CCTD)
  • 3th1 – PpCCTD + Fe+3
    
  • 1s9a – RoCCTD + Fe+3
    
  • 3o32, 3o5u – RoCCTD + Fe+3 + dichlorocatechol derivative
    
  • 3o6j – RoCCTD + Fe+3 + hydroxyquinol
    
  • 3o6r – RoCCTD + Fe+3 + pyrogallol
    
  • 2boy – RoCCTD + Fe+3 + benzhydroxamate
    
• Hydroxyquinol 1,2-dioxygenase (HQD)
  • 1tmx – PsiHQD + Fe+3 – Pimelobacter simplex
    
  • 4zxd – PsHQD - Pseudomonas
    
  • 4zxa – PsHQD + Cd+2 + benzonitrile
    
  • 4zxc – PsHQD + Fe+3
    
  • 5m22 – SpHQD + Fe+3
    
  • 5m4o – SpHQD + Fe+3 + nitrophenol
    
  • 5m26 – SpHQD + Fe+3 + hydroquinone derivative
    
  • 5m21 – SpHQD + Fe+3 + hydroxybenzoate
    
• Nitrobenzene dioxygenase (NBDO)
  • 2bmo – CtNBDO + Fe+3 + Fe2S2
    
  • 2bmq – CtNBDO + Fe+3 + Fe2S2 + nitrobenzene
    
  • 2bmr – CtNBDO + Fe+3 + Fe2S2 + nitrotoluene
    
• α-ketoglutarate-dependent dioxygenase (Alkb)
  • 3khb – hAlkb (mutant) + Co+2 + oxoglutarate
    
  • 3i3q – hAlkb + Mn+2 + oxoglutarate
    
  • 3thp – hAlkb + Mn+2 + Zn+2 + oxoglutarate
    
  • 3tht – hAlkb (mutant) + Mn+2 + Zn+2 + oxoglutarate
    
  • 3t4h, 3t4v, 3t3y – EcAlkb + Fe+3 + inhibitor – Escherichia coli
    
  • 2fdj, 2fdg – EcAlkb + Mn+2 + succinate
    
  • 4jht – EcAlkb + Mn+2 + quinoline derivative
    
  • 4rfr – EcAlkb + Mn+2 + rhein
    
  • 2fdf – EcAlkb (mutant) + Co+2 + oxoglutarate
    
  • 4zhn – EcAlkb (mutant) + Co+2 + oxoglutarate + trinucleotide
    
  • 2fd8 – EcAlkb (mutant) + Fe+2 + oxoglutarate
    
• Alkb complex with DNA
  • 3rzm, 3rzl, 3rzh, 3rzg, 3btz, 4mg2, 4mgt – hAlkb (mutant) + DNA
    
  • 3h8x, 3h8r, 3h8o, 3bty – hAlkb (mutant) + DNA + inhibitor
    
  • 3btx – hAlkb (mutant) + Mg+2 + DNA
    
  • 3i49, 3i2o – hAlkb + Fe+2 + oxoglutarate + DNA
    
  • 4nid – hAlkb + Mn+2 + oxoglutarate + DNA
    
  • 4nig, 4nih, 4nii – hAlkb (mutant) + Mn+2 + oxoglutarate + DNA
    
  • 3o1s – hAlkb + DNA
    
  • 3i3m – hAlkb + Mn+2 + oxoglutarate + DNA
    
  • 3s5a, 3s57, 3rzk, 3rzj, 3buc, 3bu0, 3bkz – hAlkb (mutant) + Mn+2 + oxoglutarate + DNA
    
  • 3o1r, 3o1p, 3o1o, 3o1m – hAlkb (mutant) + Mn+2 + oxoglutarate + DNA + inhibitor
    
  • 3bie, 3bi3, 2fdh – EcAlkb (mutant) + Mn+2 + oxoglutarate + DNA + inhibitor
    
  • 2fdi – EcAlkb + Fe+2 + oxoglutarate + DNA + inhibitor
    
  • 3khc – hAlkb (mutant) + Co+2 + oxoglutarate + DNA + inhibitor
    
  • 3o1v, 3o1u, 3o1t, 3t1s – hAlkb (mutant) + Fe+3 + succinate + DNA + inhibitor
    
• α-ketoglutarate-dependent dioxygenase homolog (Alkbh)
  • 4nj4, 4o7x – hAlkbh5 residues 66-292 + Mn
    
  • 4o61 – hAlkbh5 residues 74-294 + citrate
    
  • 4nrm – hAlkbh5 residues 66-292 + citrate + acetate
    
  • 4nro – hAlkbh5 residues 66-292 + Mn + ketoglutarate
    
  • 4oct – hAlkbh5 residues 66-292 + Mn + oxoglutarate
    
  • 4nrp – hAlkbh5 residues 66-292 + Mn + oxalylglycine
    
  • 4nrq – hAlkbh5 residues 66-292 + Mn + pyridine dicarboxylate
    
  • 4npl – zfAlkbh5 residues 38-287 + Mn + ketoglutarate – zebra fish
    
  • 4npm – zfAlkbh5 residues 38-287 + Mn + succinate
    
  • 4qkb, 4qkd – hAlkbh7 residues 17-215 (mutant) + Mn + ketoglutarate
    
  • 4qkf – hAlkbh7 residues 17-215 (mutant) + Mn + oxalylglycine
    
• α-ketoglutarate-dependent dioxygenase (Fto)
  • 4idz – hFto + Ni+2 + oxalylglycine
    
  • 4ie0, 4ie5, 4qho – hFto + Zn+2 + pyrimidine derivative
    
  • 4ie4, 4ie6 – hFto + Zn+2 + quinoline derivative
    
  • 4ie7 – hFto + Zn+2 + rhein
    
  • 4qkn – hFto + Mn+2 + meclofenamic acid
    
  • 4cxw, 4cxx, 4cxy – hFto + Ni+2 + inhibitor
    
  • 6akw – hFto + oxoglutarate + inhibitor
    
  • 5f8p, 5dab – hFto + Fe+2 + oxoglutarate + inhibitor
    
  • 4zs2, 4zs3 – hFto + Mn+2 + oxoglutarate + fluorescin
    
  • 5zmd – hFto (mutant) + Mn+2 + AMP derivative + DNA + oxalylglycine
    
  • 6eoz – EnFto + Ni+2 + cyclopeptin – Emericela nidulans
    
  • 5ybl – EnFto + Mn+2 + oxoglutarate
    
  • 5y7t, 5y7r – EnFto + Fe+3 + oxoglutarate + cyclopeptin
    
  • 5oa8, 5oa7, 5oa4 – EnFto (mutant) + Ni+2 + oxoglutarate + cyclopeptin
    
• α-ketoglutarate-dependent dioxygenase (ANDA)
  • 5zm2 – EvANDA – Emericella variicolor
    
  • 5zm4, 5zm3 – EvANDA + Fe+3 + oxoglutarate + preandiloid
    
• Leucoanthocyanidin dioxygenase (LACD)
  • 1gp5, 1gp6 – AtLACD + dihydroquercetin – Arabidopsis thaliana
    
  • 2brt – AtLACD + naringenin
    
• Methylcytosine dioxygenase (TET)
  • 5d9y, 5deu, 4nm6 – hTET2 + DNA
    
  • 4z3c – hTET3 + DNA
    
  • 5exh – mTET3 + DNA – mouse
    
• Dioxygenase extradiol family
• Homoprotocatechuate 2,3-dioxygenase (HPCD)
  • 1f1r, 1f1u – AgHPCD + Mn+2 – Arthrobacter globiformis
    
  • 1f1x, 1q0o – BfHPCD + Fe+3 – Brevibacterium fuscum
    
  • 2ig9, 3ojt, 5trx – BfHPCD + Fe+2
    
  • 3ecj, 4ghc, 5bwg, 5bwh, 4z6l, 4z6m, 4z6n, 4z6o, 4z6p, 4z6q – BfHPCD (mutant) + Fe+2
    
  • 4z6z – BfHPCD + Fe+2 + catechol derivative
    
  • 4z6r, 4z6s, 4z6t, 4z6u, 4z6v, 4z6w – BfHPCD (mutant) + Fe+2 + catechol derivative
    
  • 3bza, 3ojn – BfHPCD + Mn+2
    
  • 3ojj – BfHPCD + MCo+2
    
• HPCD complex with aromatic compound
  • 1f1v – AgHPCD + Mn+2 + dihydroxyphenyl acetate
    
  • 1q0c, 4ghg – BfHPCD + Fe+2 + dihydroxyphenyl acetate
    
  • 4ghd – BfHPCD (mutant) + Fe+2 + dihydroxyphenyl acetate
    
  • 2iga – BfHPCD + Fe+2 + O2 + reaction intermediates
    
  • 3eck – BfHPCD (mutant) + Fe+2 + reaction intermediates
    
  • 3ojk – BfHPCD + Co+2 + catechol derivative
    
  • 4ghe, 4ghf – BfHPCD (mutant) + Fe+2 + catechol derivative
    
  • 4ghh – BfHPCD + Fe+2 + catechol derivative
    
• Catechol 2,3-dioxygenase (MPC)
  • 1mpy – PpMPC + Fe+2
    
  • 3hpv – PsMPC + Fe+2
    
  • 3hpy – PsMPC + Fe+2 + catechol derivative
    
  • 3hq0 – PsMPC + Fe+3 + product
    
  • 2wl3, 2wl9 - RoMPC + Fe+3 - Rhodococcus opacus
    
  • 3lm4 – RoMPC + Fe+3 + H2O2
    
  • 5zsz – DiMPC + Fe+3 - Diaphorobacter
    
  • 5znh – DiMPC + Fe+3 + catechol derivative
    
• Naphthalene 1,2-dioxygenase (NDO)
  • 1ndo, 1o7h, 1o7w – PpNDO + Fe+3 + Fe2S2
    
  • 2hmj – PpNDO (mutant) + Fe+3 + Fe2S2
    
  • 2b1x – RoNDO + Fe+3 + Fe2S2
    
• NDO complex with aromatic compound
  • 1eg9 – PpNDO + Fe+3 + Fe2S2 + indole
    
  • 1o7g – PpNDO + Fe+3 + Fe2S2 + naphthalene
    
  • 1o7m – PpNDO + Fe+3 + Fe2S2 + O2
    
  • 1o7n – PpNDO + Fe+3 + Fe2S2 + O2 + indole
    
  • 1o7p – PpNDO + Fe+3 + Fe2S2 + dihydronaphthalene
    
  • 1uuv, 1uuw – PpNDO + Fe+3 + Fe2S2 + NO3
    
  • 2hmk, 2hml – PpNDO (mutant) + Fe+3 + Fe2S2 + phenanthrene
    
  • 2hmm, 2hmn – PpNDO (mutant) + Fe+3 + Fe2S2 + anthracene
    
  • 2hmo – PpNDO + Fe+3 + Fe2S2 + nitrotoluene
    
  • 2b24 – RoNDO + Fe+3 + Fe2S2 + indole
    
  • 4hm0, 4hm1, 4hm4, 4hm5 – PsNDO + Fe+3 + Fe2S2 + indole derivative
    
  • 4hm2, 4hm3, 4hm6, 4hm7, 4hm8 – PsNDO + Fe+3 + Fe2S2 + phenyl derivative
    
  • 4hjl – PsNDO + Fe+3 + Fe2S2 + chloronaphthalene
    
  • 4hkv – PsNDO + Fe+3 + Fe2S2 + benzamide
    
• Dihydronaphthalene 1,2-dioxygenase (HNDO)
  • 2ehz, 2ei2 – PsHNDO + Fe+2
    
  • 2ei0, 2ei1, 2ei3 – PsHNDO + Fe+2 + dihydroxybephenyl
    
• 2,3-dihydroxybiphenyl 1,2-dioxygenase (DHBP)
  • 1dhy, 1eil, 1eiq, 1eir – PsDHBP + Fe+3
    
  • 1kw3 – PsDHBP + Fe+2
    
  • 1kw8 – PsDHBP + Fe+2 + NO
    
  • 1kwb – PsDHBP (mutant)
    
  • 1han, 1kmy – BxDHBP (mutant) + Fe+3 – Burkholderia xenovorans
    
• DHBP complex with aromatic compound
  • 1knd, 1knf – BxDHBP + Fe+3 + catechol derivative
    
  • 1lgt, 1lkd – BxDHBP + Fe+2 + dihydroxybephenyl
    
  • 1kw6, 1kw9 – PsDHBP + Fe+2 + dihydroxybephenyl
    
  • 1kwc – PsDHBP (mutant) + dihydroxybephenyl
    
• Salicylate 1,2-dioxygenase (SDO)
  • 2phd – PssSDO + Fe+3 – Pseudaminobacter salicylatoxidans
    
  • 4fah, 4fbf – PssSDO (mutant) + Fe+3
    
  • 3nst – PssSDO (mutant) + Fe+2
    
  • 3njz – PssSDO + Fe+2 +salicylate
    
  • 3nvc – PssSDO (mutant) + Fe+2 +salicylate
    
  • 3nkt – PssSDO + Fe+2 +naphthoate
    
  • 3nl1 – PssSDO + Fe+2 +gentisate
    
  • 3nw4, 4fag – PssSDO (mutant) + Fe+2 +gentisate
    
• Biphenyl 1,2-dioxygenase (BDO)
  • 3gzy – CtBDO + Fe+2 + Fe2S2 – Comamonas testosteroni
    
  • 2xr8 – BxBDO + Fe+2 + Fe2S2
    
  • 2xso, 2yfi, 5aeu – BxBDO (mutant) + Fe+2 + Fe2S2
    
  • 1uli - RoBDO + Fe+2 + Fe2S2
    
  • 2gbw - SyBDO + Fe+2 + Fe2S2 + O2 – Sphingobium yanoikuyae
    
• BDO complex with aromatic compound
  • 3gzx – CtBDO + Fe+2 + Fe2S2 + biphenyl
    
  • 2xrx – BxBDO + Fe+2 + Fe2S2 + biphenyl
    
  • 2xsh, 5aew – BxBDO (mutant) + Fe+2 + Fe2S2 + biphenyl
    
  • 2yfj, 2yfl – BxBDO (mutant) + Fe+2 + Fe2S2 + dibenzofuran
    
  • 1ulj - RoBDO + Fe+2 + Fe2S2 + biphenyl
    
  • 2gbx - SyBDO + Fe+2 + Fe2S2 + biphenyl
    
• Tryptophan 2,3-dioxygenase (TDO)
  • 4pw8 - hTDO + Co+2
    
  • 5tia, 5ti9 – hTDO + heme + tryptophan
    
  • 6a4i – hTDO + heme + tryptophan + inhibitor
    
  • 1yw0 – XcTDO + Mg – Xanthomonas campestris
    
  • 2nw7 – XcTDO + heme
    
  • 4hka – TDO + heme – Drosophila melanogaster
    
  • 3bk9, 3e08 – XcTDO (mutant) + heme + tryptophan
    
  • 2nw8, 2nw9 – XcTDO + heme + Mn + tryptophan derivative
    
  • 2nox – CmTDO + heme – Cupriavidus metallidurans
    
• Cysteine dioxygenase type I (CysDO)
  • 6bgm, 6bgf, 6e87 – hCysDO + Fe+2
    
  • 2ic1, 6n42 – hCysDO + Fe+2 + cysteine
    
  • 6cdh, 6bpw, 6bpu, 6bpt – hCysDO + Fe+2 + Tyr derivative
    
  • 6cdn, 6bpx, 6bpv, 6bps – hCysDO + Fe+2 + cysteine + Tyr derivative
    
  • 6bpr – hCysDO + Fe+3 + cysteine + Tyr derivative + NO
    
  • 6n43 – hCysDO + Fe+3 + cysteine + NO
    
  • 2gh2, 4ieo, 4iep, 4ieq, 4ier, 4ies, 4iet, 4ieu, 4iev, 4iew, 4iex, 4iey, 4iez, 4jtn, 4jto, 4kwj, 4kwk, 4kwl, 2b5h – rCysDO + Fe+2 – rat
    
  • 4ubg, 4ubh, 5ezw, 5efu, 4ysf, 4yyo – rCysDO (mutant) + Fe+2
    
  • 5fdb – rCysDO (mutant)
    
  • 4yni – rCysDO
    
  • 5i0r, 4xet, 4xfb, 4xfc, 4pix – rCysDO (mutant) + Fe+3
    
  • 3eln – rCysDO + Fe+2 + cysteine derivative
    
  • 4z82 – rCysDO (mutant) + Fe+2 + cysteine derivative
    
  • 5i0u, 5i0t, 5i0s, 4xf4, 4xf9, 4xfa, 4piz – rCysDO + Fe+3 + cysteine derivative
    
  • 4xf0, 4xf1, 4xfg, 4xfh, 4xfi, 4piy – rCysDO (mutant) + Fe+3 + cysteine derivative
    
  • 4xez, 4xff – rCysDO (mutant) + Fe+3 + inhibitor
    
  • 4xf3 – rCysDO (mutant) + Fe+3 + inhibitor + cysteine
    
  • 2q4s, 2atf – mCysDO + Ni+2
    
• 4-hydroxyphenylpyruvate dioxygenase (HPPD)
  • 3isq, 5ec3 – hHPPD + Co+2
    
  • 1sqi – rHPPD + Fe+3 + inhibitor - rat
    
  • 1cjx – HPPD + Fe+2 – Pseudomonas fluorescens
    
  • 1t47 – HPPD + Fe+2 – Streptomyces avermitilis
    
  • 3zgj – HPPD + Co+2 + mandelic acid – Streptomyces coelicolor
    
  • 1sqd, 1sp9 – AtHPPD + Fe+3
    
  • 1tfz, 1tg5, 6j63, 5ywh, 5ywg - AtHPPD + Fe+3 + inhibitor
    
  • 5xgk – AtHPPD + Fe+3 + hydroxyphenylpyruvate
    
  • 6isd – AtHPPD + Fe+3 + sulcotrione
    
  • 5yy7, 5yy6, 5ywk – AtHPPD + Co+2 + benquitrione
    
  • 5ywi – AtHPPD (mutant) + Co+2 + NTBC
    
  • 1sp8 – HPPD + Fe+2 – corn
    
  • 5hmq – PpHPPD + Mg+2
    
• Quercetin 2,3-dioxygenase (QDO)
  • 1juh – AjQDO + Cu+2 – Aspergillus japonicus
    
  • 2h0v – QDO + Fe+3 – Bacillus subtilis
    
  • 1gqg, 1gqh – AjQDO + Cu+2 + inhibitor
    
  • 1h1i – AjQDO + Cu+2 + quercetin
    
  • 1h1m – AjQDO + Cu+2 + kaempferol
    
• Taurine/α-ketoglutarate dioxygenase (TauD)
  • 1gqw, 1gy9, 1os7 – EcTauD + Fe+2 + taurine + oxoglutarate
    
  • 1otj – EcTauD + taurine
    
  • 3pvj, 3v15 – PpTauD
    
  • 3v17 – PpTauD + oxoglutarate
    
  • 3r1j – HAD + Fe+3 – Mycobacterium avium
    
  • 4j5i – HAD + Fe+3 – Mycobacterium smegmatis
    
  • 3swt – HAD + Fe+3 – Mycobacterium marinum
    
  • 5keu – BxHAD + Mg+2
    
  • 5vn6 – BaHAD + Mg+2
    
• 3-hydroxyanthranilate 3,4-dioxygenase (HAD)
  • 2qnk – hHAD + Ni+2
    
  • 5tkq – hHAD + Zn+2
    
  • 5tk5 – hHAD + Fe+3
    
  • 3fe5 – HAD + Fe+3 - bovine
    
  • 1zvf – HAD + Ni+2 - yeast
    
  • 5v28, 4r52 – CmHAD + Fe+2 – Cupriavidus metallidurans
    
  • 5v27, 5v26, 6d60, 6bvr, 6bvp – CmHAD (mutant) + Fe+2
    
  • 1yfu, 4hvq, 4hvr, 4i3p, 4l2n – CmHAD + Fe+3
    
  • 4hvo – CmHAD + Fe+3 + Cu+2
    
  • 1yfw – CmHAD + Fe+3 + O2 + hydroxyanthranilate
    
  • 1yfx – CmHAD + Fe+3 + NO + hydroxyanthranilate
    
  • 1yfy – CmHAD + Fe+3 + hydroxyanthranilate
    
  • 6d62, 6d61, 6cd3, 6bvs, 6bvq – CmHAD (mutant) + Fe+2 + hydroxyanthranilate derivative
    
  • 4wzc – HAD + Fe+2 + enedioate derivative – Ralstonia metallidurans
    
• Carbazole 1,9a-dioxygenase (CDO)
  • 1vck – CDO ferredoxin component + Fe+3 + Fe2S2 – Pseudomonas resinovorans
    
  • 2de5, 2de6 – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 – Janthinobacterium
    
  • 2de7, 3vmg – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole
    
  • 3vmh – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + O2
    
  • 4nb8, 4nb9, 4nba, 4nbb, 4nbc, 4nbd, 4nbe, 4nbf, 4nbg, 4nbh – JaCDO ferredoxin and terminal oxygenase components (mutant) + Fe+2 + Fe2S2
    
  • 3vmi – JaCDO ferredoxin and terminal oxygenase components + Fe+3 + Fe2S2 + carbazole + O2
    
  • 3gcf – CDO terminal oxygenase component + Fe+2 + Fe2S2 – Nocardioides aromaticivorans
    
  • 3gkq – SpCDO terminal oxygenase component + Fe+2 + Fe2S2
    
• Homogentisate 1,2-dioxygenase (HGDO)
  • 1ey2 – hHGDO + Fe+2
    
  • 1eyb – hHGDO
    
  • 4aq2 – PpHGDO + Fe+3
    
  • 4aq6 – PpHGDO + Fe+3 + substrate
    
  • 3zds – PpHGDO + Fe+3 + O2
    
• Hydroxyethylphosphonate dioxygenase (PHPD)
  • 4yar, 3g7d – SvPHPD + Cd+2 – Streptomyces viridochromogenes
    
  • 3rzz – SvPHPD (mutant) + Cd+2
    
  • 3gbf – SvPHPD + Cd+2 + hydroxyethylphosphonate
    
  • 6b9r – PHPD + Fe+3 + hydroxyethylphosphonate - Streptomyces albus
    
• Gallate dioxygenase (GD)
  • 3wrc – SpGD + Fe+2 + dehydroxybenzoate
    
  • 3wku, 3wpm, 3wr4 – SpGD + Fe+3 + gallate
    
  • 3wr3, 3wr9 – SpGD + Fe+2 + gallate
    
  • 3wrb – SpGD (mutant) + Fe+2 + gallate
    
  • 3wr8, 3wra – SpGD + Fe+2
    
• Glyoxalase/bleomycin resistant protein/dioxygenase (GBD)
  • 2rbb – GBD – Burkholderia phytofirmans
    
  • 2rk9 – GBD – Vibrio splendidus
    
  • 3b59 – GBD – Novosphingobium aromaticivorans
    
  • 3kol – GBD – Nostoc punctiforme
    
  • 3rri – GBD – Alicyclobacillus acidocaldarius
    
  • 3vb0 – GBD – Sphingomonas wittichii
    
  • 3vcx – GBD – Pseudomonas palustris
    
  • 4g6x – CaGBD – Catenulispora acidiphila
    
  • 4n04 – CaGBD (mutant)
    
  • 4gym – GBD – Conexibacter woesei
    
  • 4hc5 – GBD – Sphaerobacter thermophilus
    
  • 4mym – GBD – Nocardioides
    
  • 4qb5 – GBD – Albidiferax ferrireducens
    
  • 4rt5 – GBD – Planctomyces limnophilus
    
  • 5ump, 5umq – StGBD – Streptomyces
    
  • 5uhj, 5ujp – GBD + Ni+2
    
  • 6bbx – StGBD + inhibitor
    
  • 5umw, 5umx, 5umw – StGBD + riboflavin
    
  • 5umy, 5w27 – StGBD + antibiotics
    
  • 5c4p, 5c68, 5cb9 – TcGBD + Ni+2 – Thermomonospora curvata
    
  • 5c6x – TcGBD + Co+2
    
  • 5v0f – TcGBD + Fe+3 + roxasone
    
  • 4z04 – GBD + Zn+2 + glutathione – Brucella abortus
    
• Procollagen-proline dioxygenase (PPD)
  • 5iat – BaPDD – Bacillus anthracis
    
  • 5iax – BaPDD + Co+2 + oxoglutarate
    
  • 5iav – BaPDD + Co+2 + malonate
    
• 1,2-dihydroxy-3-keto-methylthiopentene dioxygenase (KMTPD) or acereductone dioxygenase
  • 5i8s – mKMTPD + Ni+2 + pentanoate + valerate
    
  • 5i8t – mKMTPD + Ni+2 + lactate
    
  • 5i8y – mKMTPD + Co+2 + keto-methylthio-butyrate
    
  • 5i91 – mKMTPD + Ni+2 + keto-methylthio-butyrate
    
  • 5i93 – mKMTPD + Ni+2 + keto-pentanoate
    
  • 4qgn – hKMTPD + Fe+3
    
  • 4qgl, 4qgm – BaKMTPD + Cd+2
    
• Indoleamine 2,3-dioxygenase 1 (IAD)
  • 6azu – hIAD + heme
    
  • 6e45, 6e44 – hIAD 1 (mutant) + heme
    
  • 5ek2, 5ek3, 5ek4, 4pk5, 5xe1, 5wn8 – hIAD + heme + imidazole derivative
    
  • 4u72, 4u74, 6e42, 6e41, 6e40 – hIAD (mutant) + heme + imidazole derivative
    
  • 6f0a – hIAD + heme + imidazole derivative + Ala
    
  • 6azw, 6azv – hIAD + inhibitor
    
  • 5etw, 6mq6, 6dpr, 6dpq – hIAD + heme + inhibitor
    
  • 5wmu, 6e35 – hIAD + heme + CN + Trp
    
  • 5wmw, 6cxv, 6cxu – hIAD (mutant) + heme + CN + Trp
    
  • 5wmv – hIAD + heme + CN + indole derivative + Trp
    
  • 5wmx – hIAD (mutant) + heme + CN + indole derivative + Trp
    
  • 5whr – hIAD + heme + pyrrolydine derivative
    
  • 6e46 – hIAD 1 + heme + Trp
    
  • 6e43 – hIAD 1 (mutant) + inhibitor
    
• Thymine dioxygenase (TD)
  • 5c3o – NcTD – Neurospora crassa
    
  • 5c3p – NcTD + oxoglutarate + Ni+2
    
  • 5c3q – NcTD + oxoglutarate + Ni+2 + thymine
    
  • 5c3s – NcTD + oxoglutarate + Ni+2 + pyrimidine derivative
    
  • 5c3r – NcTD + oxoglutarate + Ni+2 + pyrimidine derivative + uracil derivative
    
• 2,4’-dihydroxyacetophenone dioxygenase (APD)
  • 5bpx, 4p9g – APD + Fe+3 – Alcaligenes
    
• Thiol dioxygenase (ThD)
  • 4tlf – PaThD + Fe+2 – Pseudomonas aeruginosa
    
  • 4wvz – PaThD (mutant) + Fe+2
    
• FT_T dioxygenase (FTTD)
  • 6d3j – ShFTTD + Co+2 + oxoglutarate – Sphingobium herbicidovorans
    
  • 6d3m – ShFTTD + Co+2 + oxoglutarate + quinoxalin
    
  • 6d3i, 6d3h – ShFTTD + Co+2 + oxoglutarate + phenoxy derivative
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman