Activin receptor

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3D structures of activin receptor

Updated on 05-May-2020

{"openlevels":0}

• Activin receptor type 1 or Activin receptor-like type 2 or Serine/threonine-protein kinase receptor R1 or ALK2
  • 5oxg - hAcvr1 kinase domain 172-499 + inhibitor - human
    
  • 6acr, 6gi6, 6gip, 6gin, 4bgg, 3q4u, 3mtf, 6t6d, 6jux, 6tnb, 6tn8, 6t8n, 6szm, 6eix, 6srh, 5oy6 - hAcvr1 kinase domain (mutant) + inhibitor
    
  • 3h9r, 4c02, 6i1s - hAcvr1 kinase domain + FKBP12 + inhibitor
    
• Activin receptor type 2
  • 1bte - Acvr2 LBD 19-134 - mouse
    
• Activin receptor type 2A
  • 4asx, 3soc, 3q4t - hAcvr2A kinase domain + inhibitor
    
  • 5nh3 - hAcvr2A LBD + antibody
    
  • 2goo, 2h64, 2h62 - mAcvr2A LBD + BMP-2 + ALK3
    
  • 1lx5 - mAcvr2A LBD + BMP-7
    
• Activin receptor type 2B
  • 2qlu - hAcvr2B kinase domain
    
  • 5ngv, 5nhr - hAcvr2B LBD + antibody
    
  • 1s4y - mAcvr2B LBD + inhibin
    
  • 1nyu - rAcvr2B LBD + inhibin - rat
    
  • 6mac - rAcvr2B LBD + GDF-11 + ALK5
    
• Activin receptor-like type 1 or Serine/threonine-protein kinase receptor R3 or ALK1
  • 2lcr - hALK1 LBD - NMR
    
  • 6sf2 - hALK1 LBD + GDF-2
    
  • 4fao - hALK1 LBD + GDF-2 + SKR3
    
  • 6sf1, 6sf3 - hALK1 LBD + BMP10
    
  • 3my0 - hALK1 kinase domain + inhibitor
    
• Activin receptor-like kinase 5 or Serine/threonine-protein kinase receptor R4 or ALK5 or TGF-beta receptor type 1 or TGFR-1 or SKR4
  • 5e8s, 1ias - hALK5 kinase domain
    
  • 5e8u, 5e8t - hALK5 kinase domain (mutant)
    
  • 2l5s - hALK5 LBD - NMR
    
  • 3kfd - hALK5 LBD + TGFR-2 LBD + TGF-beta-1
    
  • 2pjy - hALK5 LBD + TGFR-2 LBD + TGF-beta-3
    
  • 2wot, 2wou, 3hmm, 5usq, 3gxl, 5fri, 3tzm, 1vjy, 4x0m, 4x2f, 4x2g, 4x2j, 4x2k, 4x2n, 2x7o, 3faa, 3kcf, 1py5, 1rw8 - hALK5 kinase domain + inhibitor
    
  • 5e90, 5e91, 5qil, 5qik, 5qim, 6b8y, 5qu0, 5qtz, 5e8z - hALK5 kinase domain (mutant) + inhibitor
    
  • 5e8x, 5e8w - hALK5 kinase domain (mutant) + staurosporine
    
  • 5e92 - hALK5 kinase domain (mutant) + AMPPNP
    
  • 1b6c - hALK5 kinase domain + FKBP12
    
• TGF-beta receptor type 2 or TGFR-2
  • 1m9z - hTGFR-2 LBD
    
• TGF-beta receptor type 3 or TGFR-3
  • 4ajv - mTGFR-3 ZP-C domain 591-757
    
  • 3qw9 - rTGFR-3 ZP-C domain
    

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