Function
Cytochrome c oxidase (CcO) is a transmembrane protein complex found in bacteria and mitochondria. CcO is the last enzyme in the electron transport chain. [1]
- Ba3-type cytochrome c oxidase substrate is cytochrome c552 [2].
See also Hemeproteins.
Disease
CcO deficiency is a genetic condition which affects muscle weakness, muscle tone upto severe brain dysfunction in severe cases.
Structural highlights
Mammalian CcO is composed of , , and cytochrome a and a3. The fully oxidized form of molecule. . [3] Bacterial CcO is composed of 2 subunits.
3D Structures of Cytochrome c oxidase
Cytochrome c oxidase 3D structures