Fatty acid-binding protein (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells[1]. Various FABS differ in their tissue expression.
- IFABP is intestinal;
- HFABP is heart-type;
- BFABP is brain-type;
- LFABP is liver-type;
- AFABP is adipocyte;
- LMDABP is from flight muscle;
- TFABP is from testis.
Relevance
Some FABSs are linked to metabolic and inflammatory pathways.
Structural insights
The (Hydrophobic, Polar)[2].
3D structures of fatty acid-binding protein
Fatty acid-binding protein 3D structures
