Insulin aspart

From Proteopedia

(Redirected from NovoLog)

Insulin aspart, sold under the brand name NovoLog and Fiasp, among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. See also Insulin aspart and Insulin.

Hexamer of the human insulin variant B28Asp at pH 6.5 (PDB ID 4gbc).

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setting document base to "https://proteopedia.org/wiki/index.php/NovoLog"

Jmol Version: 14.31.8 2020-09-26 10:04

java.vendor: Java2Script (HTML5)

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Jmol getValue LOADSTRUCTCallback manageLoadStructCallback

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Jmol getValue MESSAGECallback msgCb

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StatusManager callback set for MESSAGECallback f=msgCb cb=MESSAGE

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FileManager opening url https://proteopedia.org/wiki/images/8/80/4gbcba.cif

The Resolver thinks MMCif

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Setting space group name to HM:P 1

biomolecule 1 operators 1,2,3 ASYM_IDs A,B,C,D,E,F,G,H,I,J,K,L,M,N

found biomolecule 1: A,B,C,D,E,F,G,H,I,J,K,L,M,N

assembly operator 1 x,y,z

assembly operator 2 -y,x-y,z

assembly operator 3 -x+y,-x,z

4GBC-assembly-1

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Invalid or missing space group operations!

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reading 2577 atoms

ModelSet: haveSymmetry:false haveUnitcells:true haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

model 1.1 alternative locations: AB

Default Van der Waals type for model set to Jmol

2577 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Jmol 14.31.8 2020-09-26 10:04 DSSP analysis for model 1.1 - 4GBC-assembly-1

W. Kabsch and C. Sander, Biopolymers, vol 22, 1983, pp 2577-2637

We thank Wolfgang Kabsch and Chris Sander for writing the DSSP software,

and we thank the CMBI for maintaining it to the extent that it was easy to

re-engineer in Java for our purposes.

Second generation DSSP 2.0 is used in this analysis. See Int. J. Mol. Sci. 2014, 15, 7841-7864; doi:10.3390/ijms15057841.

All bioshapes have been deleted and must be regenerated.

Note: This model contains alternative locations. Use 'CONFIGURATION 1' to be consistent with CMBI DSSP.

manageLoadStructCallback failed TypeError: Cannot read properties of undefined (reading 'replace')

Time for creating model: 138 ms

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RasMol pseudo-hbond calculation

180 hydrogen bonds

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Human modified insulin complex with cresol Zn+2 and Cl-; PDB ID 4gbc

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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Insulin aspart

From Proteopedia

References

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