2cag
From Proteopedia
(New page: 200px<br /> <applet load="2cag" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cag, resolution 2.7Å" /> '''CATALASE COMPOUND II...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2CAG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]] with HEM as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 2CAG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb57_1.html Catalase]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CAG OCA]]. | + | 2CAG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]] with HEM as [[http://en.wikipedia.org/wiki/ligand ligand]]. The following page contains interesting information on the relation of 2CAG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb57_1.html Catalase]]. Active as [[http://en.wikipedia.org/wiki/Catalase Catalase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6]]. Structure known Active Sites: DH and PT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CAG OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: peroxidase]] | [[Category: peroxidase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:31:17 2007'' |
Revision as of 12:26, 30 October 2007
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CATALASE COMPOUND II
Overview
Various enzymes use semi-stable ferryl intermediates and free radicals, during their catalytic cycle, amongst them haem catalases. Structures for, two transient intermediates (compounds I and II) of the NADPH-dependent, catalase from Proteus mirabilis (PMC) have been determined by, time-resolved X-ray crystallography and single crystal, microspectrophotometry. The results show the formation and transformation, of the ferryl group in the haem, and the unexpected binding of an anion, during this reaction at a site distant from the haem.
About this Structure
2CAG is a [Single protein] structure of sequence from [Proteus mirabilis] with HEM as [ligand]. The following page contains interesting information on the relation of 2CAG with [Catalase]. Active as [Catalase], with EC number [1.11.1.6]. Structure known Active Sites: DH and PT. Full crystallographic information is available from [OCA].
Reference
Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy., Gouet P, Jouve HM, Williams PA, Andersson I, Andreoletti P, Nussaume L, Hajdu J, Nat Struct Biol. 1996 Nov;3(11):951-6. PMID:8901874
Page seeded by OCA on Tue Oct 30 14:31:17 2007
Categories: Catalase | Proteus mirabilis | Single protein | Gouet, P. | Hajdu, J. | Jouve, H.M. | HEM | Heme | Hydrogen peroxide | Iron | Nadp | Oxidoreductase (h2o2 acceptor) | Peroxidase
