2p6a
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p6a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p6a RCSB], [http://www.ebi.ac.uk/pdbsum/2p6a PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p6a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p6a RCSB], [http://www.ebi.ac.uk/pdbsum/2p6a PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/INHBA_HUMAN INHBA_HUMAN]] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. [[http://www.uniprot.org/uniprot/FST_HUMAN FST_HUMAN]] Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Jardetzky, T S | + | [[Category: Jardetzky, T S]] |
| - | [[Category: Lerch, T F | + | [[Category: Lerch, T F]] |
| - | [[Category: Shimasaki, S | + | [[Category: Shimasaki, S]] |
| - | [[Category: Woodruff, T K | + | [[Category: Woodruff, T K]] |
[[Category: Activin]] | [[Category: Activin]] | ||
[[Category: Follistatin]] | [[Category: Follistatin]] | ||
Revision as of 22:50, 25 December 2014
The structure of the Activin:Follistatin 315 complex
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