4zk4
From Proteopedia
(Difference between revisions)
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==Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane== | ==Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane== | ||
| - | <StructureSection load='4zk4' size='340' side='right' caption='[[4zk4]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='4zk4' size='340' side='right'caption='[[4zk4]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4zk4]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZK4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4zk4]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZK4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TII:(5R)-1-METHYL-7-[5-(PROPAN-2-YLOXY)PYRIDIN-3-YL]-1,7-DIAZASPIRO[4.4]NONANE'>TII</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TII:(5R)-1-METHYL-7-[5-(PROPAN-2-YLOXY)PYRIDIN-3-YL]-1,7-DIAZASPIRO[4.4]NONANE'>TII</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zjt|4zjt]], [[4zk1|4zk1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zjt|4zjt]], [[4zk1|4zk1]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHRNA3, NACHRA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zk4 OCA], [http://pdbe.org/4zk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zk4 RCSB], [http://www.ebi.ac.uk/pdbsum/4zk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zk4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zk4 OCA], [http://pdbe.org/4zk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zk4 RCSB], [http://www.ebi.ac.uk/pdbsum/4zk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zk4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Aplca]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bobango, J]] | [[Category: Bobango, J]] | ||
[[Category: Talley, T T]] | [[Category: Talley, T T]] | ||
[[Category: Wu, J]] | [[Category: Wu, J]] | ||
[[Category: Acetylcholine]] | [[Category: Acetylcholine]] | ||
| + | [[Category: Acetylcholine binding protein]] | ||
[[Category: Achbp]] | [[Category: Achbp]] | ||
[[Category: Nicotinic]] | [[Category: Nicotinic]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
Revision as of 08:39, 26 June 2019
Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy-pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane
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