2mq6

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==Solution structure of Y125F mutant of eRF1 N-domain==
==Solution structure of Y125F mutant of eRF1 N-domain==
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<StructureSection load='2mq6' size='340' side='right'caption='[[2mq6]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2mq6' size='340' side='right'caption='[[2mq6]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQ6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mq6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQ6 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ETF1, ERF1, RF1, SUP45L1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq6 OCA], [https://pdbe.org/2mq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq6 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq6 OCA], [https://pdbe.org/2mq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq6 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq6 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>
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[https://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Pervushin, K]]
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[[Category: Pervushin K]]
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[[Category: Pillay, S]]
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[[Category: Pillay S]]
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[[Category: Wong, L]]
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[[Category: Wong L]]
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[[Category: Erf1]]
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[[Category: Rdc]]
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[[Category: Translation]]
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[[Category: Translation termination]]
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Revision as of 08:04, 8 March 2023

Solution structure of Y125F mutant of eRF1 N-domain

PDB ID 2mq6

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