2v1c

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==CRYSTAL STRUCTURE AND MUTATIONAL STUDY OF RECOR PROVIDE INSIGHT INTO ITS ROLE IN DNA REPAIR==
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==Crystal structure and mutational study of RecOR provide insight into its role in DNA repair==
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<StructureSection load='2v1c' size='340' side='right' caption='[[2v1c]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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<StructureSection load='2v1c' size='340' side='right'caption='[[2v1c]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2v1c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V1C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V1C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2v1c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V1C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vdd|1vdd]], [[1u5k|1u5k]], [[1w3s|1w3s]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v1c OCA], [http://pdbe.org/2v1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v1c RCSB], [http://www.ebi.ac.uk/pdbsum/2v1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v1c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v1c OCA], [https://pdbe.org/2v1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v1c RCSB], [https://www.ebi.ac.uk/pdbsum/2v1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v1c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RECR_DEIRA RECR_DEIRA]] May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity). [[http://www.uniprot.org/uniprot/Q9RW50_DEIRA Q9RW50_DEIRA]] Involved in DNA repair and RecF pathway recombination (By similarity).[HAMAP-Rule:MF_00201][SAAS:SAAS022572_004_002906]
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[https://www.uniprot.org/uniprot/RECR_DEIRA RECR_DEIRA] May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v1/2v1c_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v1/2v1c_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Deira]]
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[[Category: Deinococcus radiodurans R1]]
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[[Category: Leiros, I]]
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[[Category: Large Structures]]
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[[Category: Mcsweeney, S]]
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[[Category: Leiros I]]
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[[Category: Timmins, J]]
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[[Category: McSweeney S]]
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[[Category: Deinococcus radioduran]]
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[[Category: Timmins J]]
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[[Category: Dna binding]]
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[[Category: Dna damage]]
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[[Category: Dna recombination]]
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[[Category: Dna repair]]
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[[Category: Homologous recombination]]
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[[Category: Hypothetical protein]]
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[[Category: Metal-binding]]
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[[Category: Recfor pathway]]
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[[Category: Reco]]
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[[Category: Recombination]]
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[[Category: Recor complex]]
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[[Category: Recr]]
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[[Category: Zinc-finger]]
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Current revision

Crystal structure and mutational study of RecOR provide insight into its role in DNA repair

PDB ID 2v1c

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