2xss
From Proteopedia
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| - | [[Image:2xss.png|left|200px]] | ||
| - | + | ==Crystal structure of GAFb from the human phosphodiesterase 5== | |
| - | + | <StructureSection load='2xss' size='340' side='right'caption='[[2xss]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | === | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[2xss]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XSS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xss OCA], [https://pdbe.org/2xss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xss RCSB], [https://www.ebi.ac.uk/pdbsum/2xss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xss ProSAT]</span></td></tr> |
| - | [[2xss]] is a 2 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. | ||
==See Also== | ==See Also== | ||
| - | *[[Phosphodiesterase|Phosphodiesterase]] | + | *[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Russwurm M]] |
| - | [[Category: | + | [[Category: Schlicker C]] |
| - | [[Category: | + | [[Category: Steegborn C]] |
Current revision
Crystal structure of GAFb from the human phosphodiesterase 5
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