2j1k

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==CAV-2 FIBRE HEAD IN COMPLEX WITH CAR D1==
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<StructureSection load='2j1k' size='340' side='right' caption='[[2j1k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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==CAV-2 fibre head in complex with CAR D1==
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<StructureSection load='2j1k' size='340' side='right'caption='[[2j1k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2j1k]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Adec2 Adec2] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J1K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J1K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2j1k]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Canine_adenovirus_2 Canine adenovirus 2] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J1K FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kac|1kac]], [[1nob|1nob]], [[1p69|1p69]], [[1p6a|1p6a]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j1k OCA], [http://pdbe.org/2j1k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j1k RCSB], [http://www.ebi.ac.uk/pdbsum/2j1k PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j1k OCA], [https://pdbe.org/2j1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j1k RCSB], [https://www.ebi.ac.uk/pdbsum/2j1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j1k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPIKE_ADECT SPIKE_ADECT]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
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[https://www.uniprot.org/uniprot/SPIKE_ADECT SPIKE_ADECT] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j1k_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j1k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adec2]]
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[[Category: Canine adenovirus 2]]
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Billet, O]]
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[[Category: Large Structures]]
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[[Category: Cusack, S]]
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[[Category: Billet O]]
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[[Category: Kremer, E J]]
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[[Category: Cusack S]]
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[[Category: Lortat-Jacob, H]]
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[[Category: Kremer EJ]]
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[[Category: Seiradake, E]]
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[[Category: Lortat-Jacob H]]
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[[Category: Adenovirus]]
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[[Category: Seiradake E]]
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[[Category: Canine]]
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[[Category: Car]]
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[[Category: Cav-2]]
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[[Category: Cell adhesion]]
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[[Category: Complex]]
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[[Category: Coxsackievirus]]
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[[Category: Domain d1]]
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[[Category: Fiber]]
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[[Category: Fiber head]]
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[[Category: Fiber protein]]
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[[Category: Fibre]]
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[[Category: Fibre head]]
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[[Category: Glycoprotein]]
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[[Category: Host-virus interaction]]
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[[Category: Immunoglobulin domain]]
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[[Category: Knob]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Palmitate]]
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[[Category: Phosphorylation]]
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[[Category: Receptor]]
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[[Category: Tight junction]]
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[[Category: Transmembrane]]
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[[Category: Virus-receptor complex]]
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Current revision

CAV-2 fibre head in complex with CAR D1

PDB ID 2j1k

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